Fabrication of Cell Chip to Detect Dopamine Secretion in PC12 Cells Using Electrochemical Method
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kafi, Md. Abdul | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.contributor.author | An, Jeung Hee | - |
dc.contributor.author | Kim, Hyuncheol | - |
dc.contributor.author | Choi, Jeong-Woo | - |
dc.date.available | 2020-11-16T05:59:34Z | - |
dc.date.issued | 2011-02 | - |
dc.identifier.issn | 1546-198X | - |
dc.identifier.issn | 1546-1971 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/43500 | - |
dc.description.abstract | A cell-based chip was fabricated for in vitro label-free monitoring of dopamine secreted from neural cells. PC12 cells were grown on the chip and allowed for cyclic voltammetric measurement to detect dopamine secretion. A quasireversible redox process was successfully observed from the cellular dopamine, and the voltammetric results showed the positive relationship between the cell numbers and peak current. Since chemical dopamine added to the cell did not change the redox potential of PC12 cells, we concluded that redox peaks of cyclic voltammetry (CV) surely came from the cellular dopamine which is released by PC12 cells. In addition, a stimulatory effect of potassium and glucose on dopamine secretion in PC12 cells was investigated by CV measurement, and further investigated by immunofluorescence staining to validate electrochemical findings. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | AMER SCIENTIFIC PUBLISHERS | - |
dc.title | Fabrication of Cell Chip to Detect Dopamine Secretion in PC12 Cells Using Electrochemical Method | - |
dc.type | Article | - |
dc.identifier.doi | 10.1166/sl.2011.1438 | - |
dc.identifier.bibliographicCitation | SENSOR LETTERS, v.9, no.1, pp 147 - 151 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000288645200033 | - |
dc.identifier.scopusid | 2-s2.0-83255192679 | - |
dc.citation.endPage | 151 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 147 | - |
dc.citation.title | SENSOR LETTERS | - |
dc.citation.volume | 9 | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Cell-Chip | - |
dc.subject.keywordAuthor | Cyclic Voltammetry | - |
dc.subject.keywordAuthor | Dopamine | - |
dc.subject.keywordAuthor | Glucose and Potassium Chloride | - |
dc.subject.keywordAuthor | PC12 Cells | - |
dc.subject.keywordPlus | INDIVIDUAL CHROMAFFIN CELLS | - |
dc.subject.keywordPlus | ASCORBIC-ACID | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | GLUCOSE | - |
dc.subject.keywordPlus | EXOCYTOSIS | - |
dc.subject.keywordPlus | ELECTRODE | - |
dc.subject.keywordPlus | ADHESION | - |
dc.subject.keywordPlus | NEURONS | - |
dc.subject.keywordPlus | GROWTH | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Electrochemistry | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Electrochemistry | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.