Nanoscale fabrication of a peptide layer in cell chip to detect effects of environmental toxins on HEK293 cells
DC Field | Value | Language |
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dc.contributor.author | Kafi, Md. Abdul | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.contributor.author | Yagati, Ajay Kumar | - |
dc.contributor.author | Kim, Hyuncheol | - |
dc.contributor.author | Choi, Jeong-Woo | - |
dc.date.available | 2020-11-16T05:59:46Z | - |
dc.date.issued | 2010-12 | - |
dc.identifier.issn | 0141-5492 | - |
dc.identifier.issn | 1573-6776 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/43503 | - |
dc.description.abstract | A cysteine-terminated C(RGD)(4) peptide film was fabricated on a gold electrode for improving the attachment of cells. The electrochemical signals of cyclic voltammogram from cells on a C(RGD)(4) deposited electrode was enhanced from 0.27 to 0.49 mu A compared to a bare electrode. The developed cell-based sensor determined the effect of bisphenol-A (BPA) and dichlorodiphenyltrichloroethane (DTT) on the viability of HEK-293 cells by detecting decrease of reduction peaks (1.12-0.15 mu A for BPA and 0.81-0.29 mu A for DDT) after the treatment of environmental chemicals. This developed system can be a powerful tool for the monitoring of environmental toxicants. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Nanoscale fabrication of a peptide layer in cell chip to detect effects of environmental toxins on HEK293 cells | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s10529-010-0366-x | - |
dc.identifier.bibliographicCitation | BIOTECHNOLOGY LETTERS, v.32, no.12, pp 1797 - 1802 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000285912900005 | - |
dc.identifier.scopusid | 2-s2.0-78149406840 | - |
dc.citation.endPage | 1802 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 1797 | - |
dc.citation.title | BIOTECHNOLOGY LETTERS | - |
dc.citation.volume | 32 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | Cyclic voltammetry | - |
dc.subject.keywordAuthor | Environmental toxicants | - |
dc.subject.keywordAuthor | HEK-293 cells | - |
dc.subject.keywordAuthor | RGD peptide | - |
dc.subject.keywordAuthor | Scanning tunneling microscopy | - |
dc.subject.keywordAuthor | Surface plasmon resonance | - |
dc.subject.keywordPlus | ASSAY | - |
dc.subject.keywordPlus | RGD | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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