Detailed Information

Cited 0 time in webofscience Cited 0 time in scopus
Metadata Downloads

Electrotriggered, Spatioselective, Quantitative Gene Delivery into a Single Cell Nucleus by Au Nanowire Nanoinjector

Full metadata record
DC Field Value Language
dc.contributor.authorYoo, Seung Min-
dc.contributor.authorKang, Mijeong-
dc.contributor.authorKang, Taejoon-
dc.contributor.authorKim, Dong Min-
dc.contributor.authorLee, Sang Yup-
dc.contributor.authorKim, Bongsoo-
dc.date.available2020-12-01T09:40:09Z-
dc.date.issued2013-06-
dc.identifier.issn1530-6984-
dc.identifier.issn1530-6992-
dc.identifier.urihttps://scholarworks.bwise.kr/cau/handle/2019.sw.cau/43543-
dc.description.abstractDelivery of bioactive materials into a cell is highly important in the study of cell biology and medical treatments. Ideal nanoinjectors should be able to deliver biomaterials with high spatial resolution while causing minimum cell damage. We developed a Au nanowire (NW) nanoinjector that has the thinnest diameter (100-150 nm) among the DNA delivering devices as well as optimum mechanical properties, minimizing cell damage. Well-defined (111) single-crystalline Au surface and high electric conductivity of a Au NW nanoinjector allow precisely timed and efficient electrochemical release of DNA molecules attached on a Au NW surface. Both linear DNA and plasmid DNA were delivered separately and showed successful expression. The Au NW nanoinjector would find important biomedical applications in the fields such as gene therapy, DNA vaccination, targeted drug delivery, and probe/control of cell signaling events.-
dc.format.extent5-
dc.language영어-
dc.language.isoENG-
dc.publisherAMER CHEMICAL SOC-
dc.titleElectrotriggered, Spatioselective, Quantitative Gene Delivery into a Single Cell Nucleus by Au Nanowire Nanoinjector-
dc.typeArticle-
dc.identifier.doi10.1021/nl4003393-
dc.identifier.bibliographicCitationNANO LETTERS, v.13, no.6, pp 2431 - 2435-
dc.description.isOpenAccessN-
dc.identifier.wosid000320485100019-
dc.identifier.scopusid2-s2.0-84879101222-
dc.citation.endPage2435-
dc.citation.number6-
dc.citation.startPage2431-
dc.citation.titleNANO LETTERS-
dc.citation.volume13-
dc.type.docTypeArticle-
dc.publisher.location미국-
dc.subject.keywordAuthorAu nanowire-
dc.subject.keywordAuthornanoinjector-
dc.subject.keywordAuthorgene delivery-
dc.subject.keywordAuthorelectrical trigger-
dc.subject.keywordAuthorDNA-
dc.subject.keywordPlusSELF-ASSEMBLED MONOLAYERS-
dc.subject.keywordPlusDNA DELIVERY-
dc.subject.keywordPlusREDUCTIVE DESORPTION-
dc.subject.keywordPlusACTION-POTENTIALS-
dc.subject.keywordPlusQUANTUM DOTS-
dc.subject.keywordPlusTRANSFECTION-
dc.subject.keywordPlusPLATFORM-
dc.subject.keywordPlusAU(111)-
dc.subject.keywordPlusARRAYS-
dc.subject.keywordPlusGOLD-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalResearchAreaScience & Technology - Other Topics-
dc.relation.journalResearchAreaMaterials Science-
dc.relation.journalResearchAreaPhysics-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryChemistry, Physical-
dc.relation.journalWebOfScienceCategoryNanoscience & Nanotechnology-
dc.relation.journalWebOfScienceCategoryMaterials Science, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPhysics, Applied-
dc.relation.journalWebOfScienceCategoryPhysics, Condensed Matter-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
Files in This Item
There are no files associated with this item.
Appears in
Collections
College of ICT Engineering > School of Integrative Engineering > 1. Journal Articles

qrcode

Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.

Related Researcher

Researcher Yoo, Seung Min photo

Yoo, Seung Min
창의ICT공과대학 (융합공학부)
Read more

Altmetrics

Total Views & Downloads

BROWSE