Nickel-Catalyzed trans-Carboamination across Internal Alkynes to Access Multifunctionalized Indoles
DC Field | Value | Language |
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dc.contributor.author | Tambe, Shrikant D. | - |
dc.contributor.author | Iqbal, Naeem | - |
dc.contributor.author | Cho, Eun Jin | - |
dc.date.available | 2021-03-06T01:40:19Z | - |
dc.date.issued | 2020-11 | - |
dc.identifier.issn | 1523-7060 | - |
dc.identifier.issn | 1523-7052 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/43755 | - |
dc.description.abstract | A Ni-catalyzed reaction was developed for the synthesis of multifunctionalized indoles. The reaction proceeded through oxidative cyclization of the Ni(0)/P^N complex with an enyne system, 2-alkynyl anilinoacrylate, to provide a nickelacycle intermediate. The trans-carboamination around the internal alkyne was achieved by syn/anti-rotation of the Ni-carbenoid intermediate formed by C-N bond cleavage of the nickelacycle, and 3-alkenylated indoles were formed by C-N bond-forming reductive elimination. Notably, the synthesized indoles could be successfully transformed to functionalized carbazoles. © 2020 American Chemical Society. All rights reserved. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | American Chemical Society | - |
dc.title | Nickel-Catalyzed trans-Carboamination across Internal Alkynes to Access Multifunctionalized Indoles | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/acs.orglett.0c03148 | - |
dc.identifier.bibliographicCitation | Organic Letters, v.22, no.21, pp 8550 - 8554 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000589942900069 | - |
dc.identifier.scopusid | 2-s2.0-85095766335 | - |
dc.citation.endPage | 8554 | - |
dc.citation.number | 21 | - |
dc.citation.startPage | 8550 | - |
dc.citation.title | Organic Letters | - |
dc.citation.volume | 22 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | C-N BOND | - |
dc.subject.keywordPlus | CIS-INSERTION | - |
dc.subject.keywordPlus | MECHANISM | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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