Diastereoselective Reductive Cyclization of Allene-Tethered Ketoamines via Copper-Catalyzed Cascade Carboboronation and Protodeborylation
DC Field | Value | Language |
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dc.contributor.author | Ashraf, Muhammad Awais | - |
dc.contributor.author | Tambe, Shrikant D. | - |
dc.contributor.author | Cho, Eun Jin | - |
dc.date.accessioned | 2021-05-20T06:40:40Z | - |
dc.date.available | 2021-05-20T06:40:40Z | - |
dc.date.issued | 2021-04 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.issn | 1229-5949 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/43987 | - |
dc.description.abstract | A copper-catalyzed cascade process has been developed for the synthesis of 3-hydroxypyrrolidine derivatives in a highly diastereoselective manner. The reaction proceeded via borylative allyl copper intermediate formation from allenes; the intermediate underwent intramolecular diastereoselective cyclization followed by cascade copper-catalyzed protodeborylation, to give 3-hydroxypyrrolidines. This method could be extended to the synthesis of six-membered piperidine analogs. A series of control experiments were carried out to confirm the Cu-catalyzed facile protodeborylation of borylated homoallylic alcohols at room temperature. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Diastereoselective Reductive Cyclization of Allene-Tethered Ketoamines via Copper-Catalyzed Cascade Carboboronation and Protodeborylation | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/bkcs.12241 | - |
dc.identifier.bibliographicCitation | BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.42, no.4, pp 683 - 690 | - |
dc.identifier.kciid | ART002707755 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000615966300001 | - |
dc.identifier.scopusid | 2-s2.0-85100596268 | - |
dc.citation.endPage | 690 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 683 | - |
dc.citation.title | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.citation.volume | 42 | - |
dc.type.docType | Article | - |
dc.publisher.location | 독일 | - |
dc.subject.keywordAuthor | Copper | - |
dc.subject.keywordAuthor | Cascade catalysis | - |
dc.subject.keywordAuthor | Allene | - |
dc.subject.keywordAuthor | 3-Hydroxypyrrolidine | - |
dc.subject.keywordAuthor | Protodeborylation | - |
dc.subject.keywordPlus | SPHINGOMONAS SP HXN-200 | - |
dc.subject.keywordPlus | ASYMMETRIC-SYNTHESIS | - |
dc.subject.keywordPlus | ARYLBORONIC ACIDS | - |
dc.subject.keywordPlus | N-OXIDES | - |
dc.subject.keywordPlus | PROTODEBORONATION | - |
dc.subject.keywordPlus | PYRROLIDINE | - |
dc.subject.keywordPlus | LIGAND | - |
dc.subject.keywordPlus | STEREOCENTERS | - |
dc.subject.keywordPlus | ALKYLATION | - |
dc.subject.keywordPlus | QUATERNARY | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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