Roles of Budding Yeast Hrr25 in Recombination and Sporulation
DC Field | Value | Language |
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dc.contributor.author | Lee, Min-Su | - |
dc.contributor.author | Joo, Jeong Hwan | - |
dc.contributor.author | Kim, Keunpil | - |
dc.date.available | 2019-03-08T08:55:50Z | - |
dc.date.issued | 2017-06 | - |
dc.identifier.issn | 1017-7825 | - |
dc.identifier.issn | 1738-8872 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4403 | - |
dc.description.abstract | Hrr25, a casein kinase 1 delta/epsilon homolog in budding yeast, is essential to set up mono-orientation of sister kinetochores during meiosis. Hrr25 kinase activity coordinates sister chromatid cohesion via cohesin phosphorylation. Here, we investigated the prophase role of Hrr25 using the auxin-inducible degron system and by ectopic expression of Hrr25 during yeast meiosis. Hrr25 mediates nuclear division in meiosis I but does not affect DNA replication. We also found that initiation of meiotic double-strand breaks as well as joint molecule formation were normal in HRR25-deficient cells. Thus, Hrr25 is essential for termination of meiotic division but not homologous recombination. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY | - |
dc.title | Roles of Budding Yeast Hrr25 in Recombination and Sporulation | - |
dc.type | Article | - |
dc.identifier.doi | 10.4014/jmb.1701.01016 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY, v.27, no.6, pp 1198 - 1203 | - |
dc.identifier.kciid | ART002239983 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000405683000019 | - |
dc.identifier.scopusid | 2-s2.0-85021666498 | - |
dc.citation.endPage | 1203 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1198 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY | - |
dc.citation.volume | 27 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Homologous recombination | - |
dc.subject.keywordAuthor | Hrr25 | - |
dc.subject.keywordAuthor | Meiosis | - |
dc.subject.keywordPlus | MEIOTIC RECOMBINATION | - |
dc.subject.keywordPlus | KINASE CDC5 | - |
dc.subject.keywordPlus | MEIOSIS-I | - |
dc.subject.keywordPlus | SACCHAROMYCES-CEREVISIAE | - |
dc.subject.keywordPlus | HOMOLOG BIAS | - |
dc.subject.keywordPlus | COHESIN | - |
dc.subject.keywordPlus | PROTEINS | - |
dc.subject.keywordPlus | DNA | - |
dc.subject.keywordPlus | PROGRESSION | - |
dc.subject.keywordPlus | TRANSITION | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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