The effect of high evening blood pressure on obstructive sleep apnea–related morning blood pressure elevation: does sex modify this interaction effect?
DC Field | Value | Language |
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dc.contributor.author | Han, S.-H. | - |
dc.contributor.author | Kim, H.J. | - |
dc.contributor.author | Lee, S.-A. | - |
dc.date.accessioned | 2021-06-18T07:31:09Z | - |
dc.date.available | 2021-06-18T07:31:09Z | - |
dc.date.issued | 2019-12 | - |
dc.identifier.issn | 1520-9512 | - |
dc.identifier.issn | 1522-1709 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/44989 | - |
dc.description.abstract | Purpose: Obstructive sleep apnea (OSA) can lead to increased morning blood pressure (BP). We hypothesized that high evening BP may aggravate OSA-related morning BP elevation. Additionally, this interactional effect may be modified by sex. Methods: This retrospective, cross-sectional study included newly diagnosed OSA patients with an apnea-hypopnea index (AHI) ≥ 5 per hour on a full-night polysomnography. An analysis of covariance (ANCOVA) was used to determine whether severe OSA (AHI ≥ 30) was associated with higher morning BP than mild-to-moderate OSA (5 ≤ AHI < 30) and whether there was an interaction between apnea severity and evening BP on morning BP. To identify the sex effects, analyses were performed separately in each sex group. Results: A total of 1445 patients with an average age of 51.9 years (SD 11.7) (male 77.9% vs. female 22.1%; high evening BP group 22.4% vs. normal evening BP group 59.6%) were included in the study. Based on the ANCOVA, patients with severe OSA had significantly higher morning systolic BP (SBP) (p = 0.003), diastolic BP (DBP) (p < 0.001), and mean BP (MBP) (p < 0.001) than the mild-to-moderate group in male subjects. A significant interaction between apnea severity and evening BP was identified on morning DBP and MBP in male subjects. However, there were no differences in morning BP between severe and mild-to-moderate OSA groups in female subjects. Conclusions: In male subjects, severe OSA contributed to higher morning BP than mild-to-moderate OSA. OSA-associated morning BP elevation was more prominent in the high evening BP group than in the normal BP group. Such relations were not found in female subjects. © 2019, Springer Nature Switzerland AG. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | The effect of high evening blood pressure on obstructive sleep apnea–related morning blood pressure elevation: does sex modify this interaction effect? | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s11325-019-01869-5 | - |
dc.identifier.bibliographicCitation | Sleep and Breathing, v.23, no.4, pp 1255 - 1263 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000510403600027 | - |
dc.identifier.scopusid | 2-s2.0-85067277455 | - |
dc.citation.endPage | 1263 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1255 | - |
dc.citation.title | Sleep and Breathing | - |
dc.citation.volume | 23 | - |
dc.type.docType | Article | - |
dc.publisher.location | 독일 | - |
dc.subject.keywordAuthor | Blood pressure | - |
dc.subject.keywordAuthor | Diastolic blood pressure | - |
dc.subject.keywordAuthor | Hypertension | - |
dc.subject.keywordAuthor | Morning blood pressure | - |
dc.subject.keywordAuthor | Obstructive sleep apnea | - |
dc.subject.keywordAuthor | Sex | - |
dc.subject.keywordPlus | HYPERTENSION | - |
dc.subject.keywordPlus | ASSOCIATION | - |
dc.subject.keywordPlus | GENDER | - |
dc.subject.keywordPlus | ALDOSTERONE | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | SEVERITY | - |
dc.subject.keywordPlus | HYPOXIA | - |
dc.subject.keywordPlus | SINGLE | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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