Association of cardiovascular risk factors on myocardial perfusion and fibrosis in asymptomatic individuals: cardiac magnetic resonance study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Cha, Min Jae | - |
dc.contributor.author | Kim, Sung Mok | - |
dc.contributor.author | Kim, Hyun Su | - |
dc.contributor.author | Kim, Yiseul | - |
dc.contributor.author | Choe, Yeon Hyeon | - |
dc.date.accessioned | 2021-06-18T07:41:26Z | - |
dc.date.available | 2021-06-18T07:41:26Z | - |
dc.date.issued | 2018-11 | - |
dc.identifier.issn | 0284-1851 | - |
dc.identifier.issn | 1600-0455 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/45175 | - |
dc.description.abstract | Background: Myocardial perfusion reserve index (MPRI) and extracellular volume fraction (ECV) on cardiac magnetic resonance (CMR) are known to quantify coronary microvascular dysfunction and myocardial fibrosis, respectively. Purpose: To demonstrate that cardiovascular risk factors such as hypertension, diabetes, hyperlipidemia, and smoking are correlated with MPRI and ECV on CMR in asymptomatic individuals. Material and Methods: Between October 2013 and July 2014, 196 individuals underwent CMR. After excluding those with chest pain, arrhythmia, and obstructive coronary artery disease, participants were divided into five groups: those without risk factor (n = 26) and those with one (n = 43), two (n = 35), three (n = 24), or four (n = 6) risk factors. MPRI and ECV were obtained on perfusion CMR and pre- and post-T1 mapping, respectively. Results: A total of 134 asymptomatic individuals (109 men, 25 women; mean age = 54.4 +/- 7.08 years; body mass index [BMI] = 24.96 +/- 2.76 kg/m(2); Framingham risk score [FRS] = 7.71 +/- 5.21) were included. The Jonckheere-Terpstra test demonstrated trends of increasing BMI, FRS, and left ventricular mass index (all P values < 0.001), but decreasing MPRI (P = 0.001) with increasing numbers of risk factors. Stepwise multiple linear regression demonstrated that an increasing number of cardiovascular risk factors was an independent predictor of MPRI (P = 0.001). However, there was no significant association between the number of risk factors and ECV (P = 0.99). Conclusion: We demonstrated that an increasing number of cardiovascular risk factors is significantly associated with reduced MPRI, but not with ECV on CMR. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.title | Association of cardiovascular risk factors on myocardial perfusion and fibrosis in asymptomatic individuals: cardiac magnetic resonance study | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/0284185118757274 | - |
dc.identifier.bibliographicCitation | ACTA RADIOLOGICA, v.59, no.11, pp 1300 - 1308 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000446482500004 | - |
dc.identifier.scopusid | 2-s2.0-85044260116 | - |
dc.citation.endPage | 1308 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1300 | - |
dc.citation.title | ACTA RADIOLOGICA | - |
dc.citation.volume | 59 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Cardiac magnetic resonance | - |
dc.subject.keywordAuthor | myocardial perfusion reserve index | - |
dc.subject.keywordAuthor | extracellular volume fraction | - |
dc.subject.keywordAuthor | cardiovascular risk factor | - |
dc.subject.keywordAuthor | asymptomatic | - |
dc.subject.keywordPlus | CORONARY MICROVASCULAR DYSFUNCTION | - |
dc.subject.keywordPlus | ATHEROSCLEROSIS MESA | - |
dc.subject.keywordPlus | DISTRIBUTION VOLUME | - |
dc.subject.keywordPlus | DIABETES-MELLITUS | - |
dc.subject.keywordPlus | HEART-DISEASE | - |
dc.subject.keywordPlus | ECHO-PLANAR | - |
dc.subject.keywordPlus | BLOOD-FLOW | - |
dc.subject.keywordPlus | RESERVE | - |
dc.subject.keywordPlus | FRAMINGHAM | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.