Evaluation of contrast media concentration in aneurysm according to change of condition in digital subtraction angiography

Abstract

The purpose of study is to suggest an optimization method to improve the risk perception of the contrast media and to acquire the appropriate image by comparing and evaluating contrast media concentration with objective values. Aneurysm Blood Flow Simulator was set equal to the blood flow velocity of the cerebral blood vessels. DSA was performed using catheters and automatic injector, and the ROI(㎟) in the aneurysm was set so as not to include surrounding structures. The concentrations of contrast media and dilution of normal saline were measured according to flow rate and volume by dividing into 4 kinds according to the main component and kinds of contrast media. This study examined the significant difference using statistics program SPSS ver. 23.The mean concentration of contrast media without dilution of normal saline was the highest at 774.70 at 4ml/s-8ml, and the lowest at 3ml/s-6ml at 1479.50. There was no significant difference in the concentration of contrast media depending on catheter type (p-value> 0.05), and there was a significant difference (p-value <0.05) between contrast media injection rate and volume. There was no significant difference Visipaque 320 and Pamiray 300, Visipaque 270 and Pamiray 250 without dilution of normal saline, respectively (p-value > 0.05).It’s expected that this study could be used as fundamental data to minimize the risk by providing optimized image in describing cerebral aneurysm in clinical, and choosing proper contrast media to patient. © 2018, Indian Journal of Public Health Research and Development. All rights reserved.