Diagnostic performance of breast ultrasonography and MRI in the prediction of lymph node status after neoadjuvant chemotherapy for breast cancer
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ha, Su Min | - |
dc.contributor.author | Cha, Joo Hee | - |
dc.contributor.author | Kim, Hak Hee | - |
dc.contributor.author | Shin, Hee Jung | - |
dc.contributor.author | Chae, Eun Young | - |
dc.contributor.author | Choi, Woo Jung | - |
dc.date.accessioned | 2021-06-18T08:41:53Z | - |
dc.date.available | 2021-06-18T08:41:53Z | - |
dc.date.issued | 2017-10 | - |
dc.identifier.issn | 0284-1851 | - |
dc.identifier.issn | 1600-0455 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/45497 | - |
dc.description.abstract | Background: Neoadjuvant chemotherapy (NAC) is widely used to treat breast cancer. Sentinel lymph node biopsy has replaced axillary lymph node dissection in patients who convert to node-negative status after NAC. However, few studies have evaluated the diagnostic performance of ultrasonography and magnetic resonance imaging (MRI) in determining axillary lymph node status after NAC. Purpose: To evaluate the diagnostic performance of breast ultrasonography and MRI in determining residual metastatic axillary lymph node status after NAC for breast cancer and to identify histopathological factors affecting radiological performance. Material and Methods: This study included 157 patients who underwent initial and follow-up preoperative breast ultrasonography and MRI before NAC between January and December 2010. The sensitivity, specificity, negative and positive predictive values, and accuracy of ultrasonography, MRI, and their combinations were evaluated. Results: The sensitivity of ultrasonography, MRI, and their combination in post-NAC axillary imaging was 60.00%, 57.33%, and 65.33%, respectively; the specificity was 60.47%, 72.09%, and 60.47%, respectively. The positive predictive value was highest with MRI (78.18%). On univariate analysis, positive estrogen receptor status was associated with misdiagnosis by ultrasonography (P = 0.002), MRI (P = 0.002), and their combination (P = 0.001). When residual metastatic lymph nodes were present, lymph nodes with macrometastasis (> 2.0 mm) were associated with correct ultrasonography-based diagnosis (P = 0.0027). Conclusion: Imaging assists in predicting axillary lymph node status in patients undergoing NAC; however, is imprudent to omit sentinel lymph node biopsy or axillary lymph node dissection for staging in women determined to be nodepositive. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SAGE PUBLICATIONS LTD | - |
dc.title | Diagnostic performance of breast ultrasonography and MRI in the prediction of lymph node status after neoadjuvant chemotherapy for breast cancer | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/0284185117690421 | - |
dc.identifier.bibliographicCitation | ACTA RADIOLOGICA, v.58, no.10, pp 1198 - 1205 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000408644400006 | - |
dc.identifier.scopusid | 2-s2.0-85027460165 | - |
dc.citation.endPage | 1205 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1198 | - |
dc.citation.title | ACTA RADIOLOGICA | - |
dc.citation.volume | 58 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Neoadjuvant chemotherapy | - |
dc.subject.keywordAuthor | axillary lymph node metastasis | - |
dc.subject.keywordAuthor | breast neoplasm | - |
dc.subject.keywordAuthor | ultrasonography | - |
dc.subject.keywordAuthor | magnetic resonance imaging (MRI) | - |
dc.subject.keywordPlus | F-18-FDG PET/CT | - |
dc.subject.keywordPlus | PREOPERATIVE CHEMOTHERAPY | - |
dc.subject.keywordPlus | AMERICAN-COLLEGE | - |
dc.subject.keywordPlus | DISSECTION | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | TRIAL | - |
dc.subject.keywordPlus | ULTRASOUND | - |
dc.subject.keywordPlus | ALLIANCE | - |
dc.subject.keywordPlus | SUBTYPES | - |
dc.subject.keywordPlus | THERAPY | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.