Dixon 정량 화학적 변위 자기공명영상을 이용한 척추 골수 지방함량과이중에너지 방사선 흡수법의 BMD 값의 비교
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤인영 | - |
dc.contributor.author | 이화연 | - |
dc.contributor.author | 김재균 | - |
dc.date.accessioned | 2021-06-18T10:42:22Z | - |
dc.date.available | 2021-06-18T10:42:22Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 2384-1095 | - |
dc.identifier.issn | 2384-1109 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/46146 | - |
dc.description.abstract | Purpose : The purpose of this study was to determine whether there is a significant correlation between vertebral marrow fat fraction measured using Dixon quantitative chemical shift MRI (QCSI) and BMD on dual-energy X-ray absorptiometry (DXA). Materials and Methods: This retrospective study included 68 healthy individuals [mean age, 50.7 years; range, 25-76; male/female (M/F) = 36/32] who underwent DXA of the L-spine and whole body MRI including QCSI of the L-spine and chemical shift MRI of the liver. The enrolled individuals were divided into subgroups according to sex and T-score [i.e., normal bone density (M/F=27/23) and osteopenia (M/F=9/9)]. Vertebral marrow (Dixon QCSI, TR/TE 10.2/4.8 ms) and hepatic fat fractions (chemical shift technique, TR/TE 110/4.9 and 2.2 ms) were calculated on MRI. We evaluated whether there were significant differences in age, body mass index (BMI), vertebral marrow fat fraction, or hepatic fat fraction among the subgroups. Whether or not the participant had reached menopause was also evaluated in females. The correlations among variables (i.e., age, BMI, vertebral marrow and hepatic fat fractions, BMD) were evaluated using Spearman’s correlation method. Results: There were no significant differences in age, BMI, or vertebral marrow and hepatic fat fractions between the two male subgroups (normal bone density vs. osteopenia). In female subjects, mean age in the osteopenic subgroup was greater than that in the normal subgroup (p=0.01). Presence of menopause was more common in the osteopenic subgroup [77.8% (7/9)] than the normal subgroup [26.1% (6/23), p<0.05]. The other variables showed no significant difference between female subgroups. The only significant correlation with marrow fat fraction after partial correlation analysis was that with age in the female subjects (r=0.43, p<0.05). Conclusion: The vertebral marrow fat fraction calculated using the Dixon QCSI does not precisely reflect the mild decrease in BMD for either sex. | - |
dc.format.extent | 9 | - |
dc.publisher | 대한자기공명의과학회 | - |
dc.title | Dixon 정량 화학적 변위 자기공명영상을 이용한 척추 골수 지방함량과이중에너지 방사선 흡수법의 BMD 값의 비교 | - |
dc.title.alternative | Correlation Between Vertebral Marrow Fat Fraction Measured Using Dixon Quantitative Chemical Shift MRI and BMD Value on Dual-energy X-ray Absorptiometry | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Investigative Magnetic Resonance Imaging, v.16, no.1, pp 16 - 24 | - |
dc.identifier.kciid | ART001659683 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 24 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 16 | - |
dc.citation.title | Investigative Magnetic Resonance Imaging | - |
dc.citation.volume | 16 | - |
dc.subject.keywordAuthor | Bone mineral density | - |
dc.subject.keywordAuthor | Bone marrow fat fraction | - |
dc.subject.keywordAuthor | Hepatic fat fraction | - |
dc.subject.keywordAuthor | aging Magnetic resonance imaging (MRI) | - |
dc.description.journalRegisteredClass | kci | - |
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