Anti-diabetic functional food with wasted litchi seed and standard of quality control
DC Field | Value | Language |
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dc.contributor.author | Choi, Se-Ah | - |
dc.contributor.author | Lee, Ji Eun | - |
dc.contributor.author | Kyung, Min Ji | - |
dc.contributor.author | Youn, Ju Hee | - |
dc.contributor.author | Oh, Jeong Bin | - |
dc.contributor.author | Whang, Wan Kyunn | - |
dc.date.available | 2019-03-08T08:58:07Z | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 2468-0834 | - |
dc.identifier.issn | 2468-0842 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4629 | - |
dc.description.abstract | The prevalence of diabetes has become a huge health burden in parts of quality of life and economic cost for overcoming this chronic disease. We followed a bioactivity-guided isolation using alpha-glucosidase inhibitory assay, four major compounds were isolated, and their structures were elucidated using nuclear magnetic resonance, mass spectrometry, and ultra-performance liquid chromatography quadrupole time of flight mass spectrometry in litchi seed. As a result, the IC50 of alpha-glucosidase inhibitory assay of the crude extract, sugar-removed layer, pavetannin B2, procyanidin A2, and acarbose was 0.691 mu g/mL, 3.686 mu g/mL, 0.04 mu M, 0.08 mu M, and 55.845 mu g/mL, respectively. With those compounds, we examined the protein tyrosine phosphatase 1B inhibitory activity. And the IC50 of pavetannin B2, procyanidin A2, and ursolic acid was 450.295, 338.257, and 19.686 mu M, respectively. Contents analysis method for bioactive compounds, which can be used in manufacturing for extract preparations, was established. The findings of this study, litchi seed can be a cost-effective medicinal food in terms of recyclable resources in the litchi food industry and as a natural alternative medicine against type-2 diabetes. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY | - |
dc.title | Anti-diabetic functional food with wasted litchi seed and standard of quality control | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s13765-017-0269-9 | - |
dc.identifier.bibliographicCitation | APPLIED BIOLOGICAL CHEMISTRY, v.60, no.2, pp 197 - 204 | - |
dc.identifier.kciid | ART002216213 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000399229100013 | - |
dc.identifier.scopusid | 2-s2.0-85015653204 | - |
dc.citation.endPage | 204 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 197 | - |
dc.citation.title | APPLIED BIOLOGICAL CHEMISTRY | - |
dc.citation.volume | 60 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | alpha-Glucosidase inhibitory assay | - |
dc.subject.keywordAuthor | Anti-diabetic agent | - |
dc.subject.keywordAuthor | Bioactivity-guided isolation | - |
dc.subject.keywordAuthor | Litchi seed | - |
dc.subject.keywordAuthor | Protein tyrosine phosphatase 1B inhibitory assay | - |
dc.subject.keywordAuthor | Quality control standard | - |
dc.subject.keywordPlus | ALPHA-GLUCOSIDASE | - |
dc.subject.keywordPlus | ANTIOXIDANT | - |
dc.subject.keywordPlus | PROCYANIDINS | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | CHINENSIS | - |
dc.subject.keywordPlus | FRUIT | - |
dc.subject.keywordPlus | MICE | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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