Electrochemical Detection of Dopamine Using 3D Porous Graphene Oxide/Gold Nanoparticle Composites
DC Field | Value | Language |
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dc.contributor.author | Choo, Sung-Sik | - |
dc.contributor.author | Kang, Ee-Seul | - |
dc.contributor.author | Song, Inbeom | - |
dc.contributor.author | Lee, Donghyun | - |
dc.contributor.author | Choi, Jeong-Woo | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.date.available | 2019-03-08T08:58:18Z | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 1424-8220 | - |
dc.identifier.issn | 1424-3210 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4648 | - |
dc.description.abstract | The detection of dopamine in a highly sensitive and selective manner is crucial for the early diagnosis of a number of neurological diseases/disorders. Here, a report on a new platform for the electrochemical detection of dopamine with a considerable accuracy that comprises a 3D porous graphene oxide (pGO)/gold nanoparticle (GNP)/pGO composite-modified indium tin oxide (ITO) is presented. The pGO was first synthesized and purified by ultrasonication and centrifugation, and it was then further functionalized on the surface of a GNP-immobilized ITO electrode. Remarkably, owing to the synergistic effects of the pGO and GNPs, the 3D pGO-GNP-pGO-modified ITO electrode showed a superior dopamine-detection performance compared with the other pGO-or GNP-modified ITO electrodes. The linear range of the newly developed sensing platform is from 0.1 mu M to 30 mu M with a limit of detection (LOD) of 1.28 mu M, which is more precise than the other previously reported GO-functionalized electrodes. Moreover, the 3D pGO-GNP-pGO-modified ITO electrodes maintained their detection capability even in the presence of several interfering molecules (e.g., ascorbic acid, glucose). The proposed platform of the 3D pGO-GNP-pGO-modified ITO electrode could therefore serve as a competent candidate for the development of a dopamine-sensing platform that is potentially applicable for the early diagnosis of various neurological diseases/disorders. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI AG | - |
dc.title | Electrochemical Detection of Dopamine Using 3D Porous Graphene Oxide/Gold Nanoparticle Composites | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/s17040861 | - |
dc.identifier.bibliographicCitation | SENSORS, v.17, no.4 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000400822900202 | - |
dc.identifier.scopusid | 2-s2.0-85018496202 | - |
dc.citation.number | 4 | - |
dc.citation.title | SENSORS | - |
dc.citation.volume | 17 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | graphene oxide | - |
dc.subject.keywordAuthor | porous structure | - |
dc.subject.keywordAuthor | gold nanoparticles | - |
dc.subject.keywordAuthor | indium tin oxide | - |
dc.subject.keywordAuthor | neurotransmitters | - |
dc.subject.keywordAuthor | dopamine | - |
dc.subject.keywordAuthor | composites | - |
dc.subject.keywordAuthor | electrochemical detection | - |
dc.subject.keywordPlus | GLASSY-CARBON ELECTRODE | - |
dc.subject.keywordPlus | ASCORBIC-ACID | - |
dc.subject.keywordPlus | SELECTIVE DETECTION | - |
dc.subject.keywordPlus | URIC-ACID | - |
dc.subject.keywordPlus | GOLD NANOPARTICLES | - |
dc.subject.keywordPlus | NANOTUBE COMPOSITE | - |
dc.subject.keywordPlus | SENSOR | - |
dc.subject.keywordPlus | DIFFERENTIATION | - |
dc.subject.keywordPlus | SEROTONIN | - |
dc.subject.keywordPlus | BRAIN | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Engineering, Electrical & Electronic | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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