Prevalence of hepatitis E virus antibodies in Canadian swine herds and identification of a novel variant of swine hepatitis E virus
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yoo, D | - |
dc.contributor.author | Willson, P | - |
dc.contributor.author | Pei, YL | - |
dc.contributor.author | Hayes, MA | - |
dc.contributor.author | Deckert, A | - |
dc.contributor.author | Dewey, CE | - |
dc.contributor.author | Friendship, RM | - |
dc.contributor.author | Yoon, YH | - |
dc.contributor.author | Gottschalk, M | - |
dc.contributor.author | Yason, C | - |
dc.contributor.author | Giulivi, A | - |
dc.date.accessioned | 2021-06-18T14:41:16Z | - |
dc.date.available | 2021-06-18T14:41:16Z | - |
dc.date.issued | 2001-11 | - |
dc.identifier.issn | 1071-412X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/47224 | - |
dc.description.abstract | Swine hepatitis E virus is a newly identified potentially zoonotic virus from pigs of particular concern for possible direct transmission to a human xenotransplant recipient by organ transplantation. In the present study, prevalence of serum antibodies to hepatitis E virus was examined in Canadian swine herds. A total of 998 serum samples collected from 6-month-old healthy slaughter hogs were examined by enzyme immunoassay and Western blot analysis for antibodies to the recombinant open reading frame 3 (ORF3) protein of hepatitis E virus expressed in Escherichia coli. These samples represented more than 80 different swine production units from five major swine-producing provinces across Canada. From this study, 594 samples (59.4%) were found to be positive for hepatitis E virus antibody. The seroprevalence was higher in Quebec (88.8%) and Ontario (80.1%) than in Alberta and Saskatchewan (38.3%). By PCR using a pair of oligonucleotide primers deduced from the ORF2 sequence of human hepatitis E virus, a specific hepatitis E virus sequence was recovered from feces of pigs. The nucleotide sequence identity between the U.S. swine hepatitis E virus and the Canadian isolate (SK3) was only 85.8%, suggesting that genotypic variations may exist in swine hepatitis E virus in North America. Among 165 serum samples collected from humans in Saskatchewan, 2.4% were found to be positive for antibodies to the hepatitis E virus ORF3 protein. Our data indicate that hepatitis E virus is highly prevalent in commercial swine populations in Canada and support the suggestion that the swine hepatitis E virus may be an important zoonotic agent for humans. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | AMER SOC MICROBIOLOGY | - |
dc.title | Prevalence of hepatitis E virus antibodies in Canadian swine herds and identification of a novel variant of swine hepatitis E virus | - |
dc.type | Article | - |
dc.identifier.doi | 10.1128/CDLI.8.6.1213-1219.2001 | - |
dc.identifier.bibliographicCitation | CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, v.8, no.6, pp 1213 - 1219 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000172036400030 | - |
dc.identifier.scopusid | 2-s2.0-0034762779 | - |
dc.citation.endPage | 1219 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1213 | - |
dc.citation.title | CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY | - |
dc.citation.volume | 8 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | OPEN READING FRAME-2 | - |
dc.subject.keywordPlus | E INFECTION | - |
dc.subject.keywordPlus | UNITED-STATES | - |
dc.subject.keywordPlus | PHYLOGENETIC ANALYSIS | - |
dc.subject.keywordPlus | SPORADIC HEPATITIS | - |
dc.subject.keywordPlus | MOLECULAR-CLONING | - |
dc.subject.keywordPlus | VIRAL-HEPATITIS | - |
dc.subject.keywordPlus | FUSION PROTEINS | - |
dc.subject.keywordPlus | BLOOD-DONORS | - |
dc.subject.keywordPlus | NON-A | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.