Characterization of chromosomal aberrations in human gastric carcinoma cell lines using chromosome painting
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Chun, YH | - |
dc.contributor.author | Kil, JI | - |
dc.contributor.author | Suh, YS | - |
dc.contributor.author | Kim, SH | - |
dc.contributor.author | Kim, H | - |
dc.contributor.author | Park, SH | - |
dc.date.accessioned | 2021-06-18T14:43:39Z | - |
dc.date.available | 2021-06-18T14:43:39Z | - |
dc.date.issued | 2000-05 | - |
dc.identifier.issn | 0165-4608 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/47368 | - |
dc.description.abstract | Using chromosome painting, a study of chromosomal abnormalities was performed in six gastric carcinoma cell lines (SNU-484, 601, 620, 638, 668, 719) from Korean patients. Each carcinoma cell line had unique modal karyotypic characteristics and showed a variable number of numerical and structural clonal cytogenetic aberrations. SNU-484, SNU-620, and SNU-668 had near-triploidy; SNU-601, SNU-638, and SNU-719 had near-diploidy. The origins of the marker chromosomes of these cell lines it ere identified by fluorescence in situ hybridization with constructed painting probes. In all of six cell lines, rearrangement of chromosome 17 resulting in partial deletion of 17p (and/or partial duplication of 17q) was found. The most frequent marker ri as a par tial gain of chromosome 7 with the breakpoints on 7q22 and 7q31. The nonrandom rearrangements of chromosomes Mere also determined on 1q32, 5q11-q22, 8q, 14q22, 14q34, and 15q15; suggesting that they may be the candidate regions for the isolation of the genes related to gastric cancer. (C) 2000 Elsevier Science Inc. All rights reserved. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Characterization of chromosomal aberrations in human gastric carcinoma cell lines using chromosome painting | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/S0165-4608(99)00217-4 | - |
dc.identifier.bibliographicCitation | CANCER GENETICS AND CYTOGENETICS, v.119, no.1, pp 18 - 25 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000087079600004 | - |
dc.identifier.scopusid | 2-s2.0-0034020383 | - |
dc.citation.endPage | 25 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 18 | - |
dc.citation.title | CANCER GENETICS AND CYTOGENETICS | - |
dc.citation.volume | 119 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordPlus | IN-SITU HYBRIDIZATION | - |
dc.subject.keywordPlus | GASTROINTESTINAL STROMAL TUMORS | - |
dc.subject.keywordPlus | COPY NUMBER CHANGES | - |
dc.subject.keywordPlus | LONG ARM | - |
dc.subject.keywordPlus | CYTOGENETIC FINDINGS | - |
dc.subject.keywordPlus | INTESTINAL-TYPE | - |
dc.subject.keywordPlus | FREQUENT LOSS | - |
dc.subject.keywordPlus | CANCER | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | ADENOCARCINOMA | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalResearchArea | Genetics & Heredity | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.relation.journalWebOfScienceCategory | Genetics & Heredity | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.