Endovascular Treatment Versus Best Medical Therapy in Acute Ischemic Stroke Patients with Mild Symptoms
DC Field | Value | Language |
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dc.contributor.author | Nicholson, P. | - |
dc.contributor.author | Byun, Jun Soo | - |
dc.contributor.author | Lu, H. | - |
dc.contributor.author | Hilditch, C.A. | - |
dc.contributor.author | Brinjikji, W. | - |
dc.contributor.author | Agid, R. | - |
dc.contributor.author | Casaubon, L.K. | - |
dc.contributor.author | Krings, T. | - |
dc.contributor.author | Schaafsma, J.D. | - |
dc.contributor.author | Mendes-Pereira, V. | - |
dc.date.accessioned | 2021-07-20T04:43:07Z | - |
dc.date.available | 2021-07-20T04:43:07Z | - |
dc.date.issued | 2020-12 | - |
dc.identifier.issn | 1878-8750 | - |
dc.identifier.issn | 1878-8769 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/47679 | - |
dc.description.abstract | Background: The benefit of endovascular treatment (EVT) for acute ischemic stroke patients with mild deficits is unknown. We sought to evaluate the natural history of patients with a low National Institute of Health Stroke Score (NIHSS) and an intracranial occlusion. Methods: We included patients with a computed tomography angiogram–proven intracranial arterial occlusion who presented within 24 hours of symptom onset with an NIHSS of ≤6. We compared outcomes of patients who were treated with EVT and those who were not by performing propensity score–matched analysis. Primary outcome was modified Rankin score (mRS) at 90 days. Results: A total of 66 patients were included: 38 were men (57.6%) with a median age of 69 (interquartile range [IQR], 57–79.5) years. Median NIHSS was 3 (IQR, 2–5). Median time from symptom onset to presentation was 2.87 hours (IQR, 1.3–5.9). Forty of the total cohort underwent best medical therapy alone (60.6%), whereas 26 underwent EVT (39.4%). Nineteen of the 26 patients who underwent EVT had a good clinical outcome (mRS ≤2) (73.1%), compared with 29 of 40 best medical therapy patients (72.5%) (odds ratio, 0.833 with 95% confidence interval, 0.263–2.631; P = 0.755). Following propensity score adjustment there was a tendency toward lower mRS following EVT (P = 0.051). Conclusions: Despite the higher number of proximal occlusions in the EVT group, overall outcomes were similar, with >70% of patients in each cohort having a good outcome at 90 days. © 2020 Elsevier Inc. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier Inc. | - |
dc.title | Endovascular Treatment Versus Best Medical Therapy in Acute Ischemic Stroke Patients with Mild Symptoms | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.wneu.2020.09.080 | - |
dc.identifier.bibliographicCitation | World Neurosurgery, v.144, pp 837 - 841 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000600668300098 | - |
dc.identifier.scopusid | 2-s2.0-85092230535 | - |
dc.citation.endPage | 841 | - |
dc.citation.startPage | 837 | - |
dc.citation.title | World Neurosurgery | - |
dc.citation.volume | 144 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | EVT | - |
dc.subject.keywordAuthor | Low NIHSS | - |
dc.subject.keywordAuthor | Medical management | - |
dc.subject.keywordAuthor | Mild stroke | - |
dc.subject.keywordAuthor | Stroke | - |
dc.subject.keywordPlus | MECHANICAL THROMBECTOMY | - |
dc.subject.keywordPlus | VESSEL OCCLUSION | - |
dc.subject.keywordPlus | NIHSS SCORE | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.subject.keywordPlus | SAFETY | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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