Analysis of factors influencing the degree of detectability on diffusion-weighted MRI and diffusion background signals in patients with invasive breast cancer
DC Field | Value | Language |
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dc.contributor.author | Hahn, Soo Yeon | - |
dc.contributor.author | Ko, Eun Sook | - |
dc.contributor.author | Han, Boo-Kyung | - |
dc.contributor.author | Lim, Yaeji | - |
dc.contributor.author | Gu, Seonhye | - |
dc.contributor.author | Ko, Eun Young | - |
dc.date.accessioned | 2021-08-13T01:40:17Z | - |
dc.date.available | 2021-08-13T01:40:17Z | - |
dc.date.issued | 2016-07 | - |
dc.identifier.issn | 0025-7974 | - |
dc.identifier.issn | 1536-5964 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/48263 | - |
dc.description.abstract | To determine the factors influencing the degree of detectability of lesions and diffusion background signals on magnetic resonance diffusion-weighted imaging (DWI) in invasive breast cancer. Institutional review board approval was obtained and patient consent was waived. Patients with newly diagnosed invasive ductal carcinoma, who underwent preoperative breast magnetic resonance imaging with DWI were included in this study (n=167). Lesion detectability on DWI and contrast-enhanced subtracted T1-weighted images, the degree of background parenchymal enhancement (BPE), and diffusion background signal were qualitatively rated. Detectability of lesions on DWI was compared with clinicopathological findings including menopausal status, mammographic density, and molecular subtype of breast cancer. Multivariate linear regression analysis was performed to determine variables independently associated with detectability of lesions on DWI and diffusion background signals. Univariate analysis showed that the detectability of lesions on DWI was significantly associated with lesion size (P=0.001), diffuse background signal (P<0.0001), and higher detectability scores for contrast-enhanced T1-weighted subtraction images (P=0.000). The degree of diffusion background signal was significantly affected by age (P<0.0001), BPE (P<0.0001), mammographic density (P=0.002), and menopausal status (P<0.0001). On multivariate analysis, the diffusion background signal (P<0.0001) and histologic grade (P<0.0001) were correlated with the detectability on DWI of invasive breast cancer. Only BPE was correlated with the amount of diffusion background signal on DWI (P<0.0001). For invasive breast cancers, detectability on DWI was significantly affected by the diffusion background signal. BPE, menopausal status, menstrual cycle, or mammographic density did not show statistically significant correlation with the diffusion detectability of lesions on DWI. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | LIPPINCOTT WILLIAMS & WILKINS | - |
dc.title | Analysis of factors influencing the degree of detectability on diffusion-weighted MRI and diffusion background signals in patients with invasive breast cancer | - |
dc.type | Article | - |
dc.identifier.doi | 10.1097/MD.0000000000004086 | - |
dc.identifier.bibliographicCitation | MEDICINE, v.95, no.27 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000380372400046 | - |
dc.identifier.scopusid | 2-s2.0-84978761723 | - |
dc.citation.number | 27 | - |
dc.citation.title | MEDICINE | - |
dc.citation.volume | 95 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | breast cancer | - |
dc.subject.keywordAuthor | diffusion background signal | - |
dc.subject.keywordAuthor | diffusion-weighted imaging | - |
dc.subject.keywordAuthor | lesion detectability | - |
dc.subject.keywordAuthor | magnetic resonance imaging | - |
dc.subject.keywordPlus | PARENCHYMAL ENHANCEMENT | - |
dc.subject.keywordPlus | DIFFERENTIAL-DIAGNOSIS | - |
dc.subject.keywordPlus | LESIONS | - |
dc.subject.keywordPlus | COEFFICIENT | - |
dc.subject.keywordPlus | MAMMOGRAPHY | - |
dc.subject.keywordPlus | METAANALYSIS | - |
dc.subject.keywordPlus | MULTICENTER | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | IMPACT | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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