Severe glyphosate-surfactant intoxication: successful treatment with continuous renal replacement therapy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, D. H. | - |
dc.contributor.author | Choi, Y. H. | - |
dc.date.available | 2019-03-08T09:39:06Z | - |
dc.date.issued | 2017-01 | - |
dc.identifier.issn | 1024-9079 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/4972 | - |
dc.description.abstract | Glyphosate-surfactant is one of the most commonly used herbicides in the world. Its key component, glyphosate, is a competitive inhibitor of the shikimate pathway, a metabolic pathway found only in plants. However, severe intoxication, including lethal cases by ingestion of, glyphosate-surfactant has been reported. We describe the full recovery of two patients from glyphosate-polyoxyethyleneamine surfactant intoxication and multi-organ system failure following continuous renal replacement therapy. Both patients developed persistent shock, acute kidney injury, lactic acidosis, hyperkalaemia and multi-organ failure despite of resuscitation. We believe that continuous renal replacement therapy should be initiated immediately for removal of glyphosate-polyoxyethyleneamine surfactant in patients with signs of cardiopulmonary compromise, lactic acidosis, and renal failure. We propose the addition of glyphosate-polyoxyethyleneamine surfactant to the list of toxins for which early haemodialysis should be indicated. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MEDCOM LTD | - |
dc.title | Severe glyphosate-surfactant intoxication: successful treatment with continuous renal replacement therapy | - |
dc.type | Article | - |
dc.identifier.doi | 10.1177/102490791702400107 | - |
dc.identifier.bibliographicCitation | HONG KONG JOURNAL OF EMERGENCY MEDICINE, v.24, no.1, pp 40 - 44 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000393349000007 | - |
dc.identifier.scopusid | 2-s2.0-85010906079 | - |
dc.citation.endPage | 44 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 40 | - |
dc.citation.title | HONG KONG JOURNAL OF EMERGENCY MEDICINE | - |
dc.citation.volume | 24 | - |
dc.type.docType | Article | - |
dc.publisher.location | 중국 | - |
dc.subject.keywordAuthor | Glycine | - |
dc.subject.keywordAuthor | herbicide | - |
dc.subject.keywordAuthor | human | - |
dc.subject.keywordAuthor | multiple organ failure | - |
dc.subject.keywordAuthor | poisoning | - |
dc.subject.keywordPlus | HERBICIDE INTOXICATION | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.relation.journalResearchArea | Emergency Medicine | - |
dc.relation.journalWebOfScienceCategory | Emergency Medicine | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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