Property modulation of the alginate-based hydrogel via semi-interpenetrating polymer network (semi-IPN) with poly(vinyl alcohol)
DC Field | Value | Language |
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dc.contributor.author | Kim, Y.J. | - |
dc.contributor.author | Min, Junhong | - |
dc.date.accessioned | 2021-11-25T07:40:08Z | - |
dc.date.available | 2021-11-25T07:40:08Z | - |
dc.date.issued | 2021-12-15 | - |
dc.identifier.issn | 0141-8130 | - |
dc.identifier.issn | 1879-0003 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/51845 | - |
dc.description.abstract | Hydrogels have been demonstrated as an attractive tool due to their extraordinary water-absorbing property. Specifically, hydrogels composed of natural polymers like polysaccharides have long been the ideal candidate because they are abundant, affordable, biocompatible, and biodegradable. However, there are unmet requirements in some practical applications because they are usually brittle and unstable. Most efforts to enhance their stability have caused unintended loss of inherent advantages, including biocompatibility and biodegradability. To balance this trade-off, here we investigate the way to modulate the property of alginate-based hydrogels by hybridizing with poly(vinyl alcohol) (PVA) via a semi-interpenetrating polymer network (semi-IPN). Thanks to the synergetic effect between alginate and PVA with a semi-IPN structure, the advantages of the alginate-based hydrogel were substantially preserved while its disadvantages were comparatively covered. We tested the stimuli-responsive behavior, degradability, mechanical stability, and physicochemical stability of the present hydrogel and verified their property was modulated by the hybridization ratio between alginate and PVA. Thereafter, long-term durability was also evaluated under a non-ideal and complex aqueous environment to prove their physiological stability enough to outlast under practical or engineering conditions. Considering that the properties were by and large controllable without losing the advantages of polysaccharides, we anticipate the present approach for the hydrogel design and property tuning methods paves the way for the value-added applications for natural hydrogels in various fields. © 2021 Elsevier B.V. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier B.V. | - |
dc.title | Property modulation of the alginate-based hydrogel via semi-interpenetrating polymer network (semi-IPN) with poly(vinyl alcohol) | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.ijbiomac.2021.11.069 | - |
dc.identifier.bibliographicCitation | International Journal of Biological Macromolecules, v.193, pp 1068 - 1077 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000729557300006 | - |
dc.identifier.scopusid | 2-s2.0-85119266844 | - |
dc.citation.endPage | 1077 | - |
dc.citation.startPage | 1068 | - |
dc.citation.title | International Journal of Biological Macromolecules | - |
dc.citation.volume | 193 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | Alginate | - |
dc.subject.keywordAuthor | Hydrogel | - |
dc.subject.keywordAuthor | Interpenetrating polymer network | - |
dc.subject.keywordAuthor | Poly(vinyl alcohol) | - |
dc.subject.keywordAuthor | Polysaccharide | - |
dc.subject.keywordPlus | POLYVINYL-ALCOHOL | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | TOUGH | - |
dc.subject.keywordPlus | SCAFFOLDS | - |
dc.subject.keywordPlus | MEMBRANES | - |
dc.subject.keywordPlus | TOXICITY | - |
dc.subject.keywordPlus | REMOVAL | - |
dc.subject.keywordPlus | DRUGS | - |
dc.subject.keywordPlus | CHIP | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Applied | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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