Association between blood mercury levels and non-alcoholic fatty liver disease in non-obese populations: The korean national environmental health survey (konehs) 2012–2014
DC Field | Value | Language |
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dc.contributor.author | Yang, Y.-J. | - |
dc.contributor.author | Yang, E.-J. | - |
dc.contributor.author | Park, K. | - |
dc.contributor.author | Oh, S. | - |
dc.contributor.author | Kim, T. | - |
dc.contributor.author | Hong, Y.-P. | - |
dc.date.accessioned | 2021-12-06T06:40:21Z | - |
dc.date.available | 2021-12-06T06:40:21Z | - |
dc.date.issued | 2021-06 | - |
dc.identifier.issn | 1661-7827 | - |
dc.identifier.issn | 1660-4601 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/52266 | - |
dc.description.abstract | Mercury is widely distributed in the environment, and a plausible association between mercury exposure and hepatic damage has been reported. Non-alcoholic fatty liver disease (NAFLD), which comprises a spectrum of liver diseases, has recently been recognized in non-obese subjects. However, there have been no studies on the relationship between internal mercury levels and NAFLD in non-obese individuals. Therefore, we investigated the association between blood mercury levels and NAFLD in non-obese subjects. Cross-sectional data (n = 5919) were obtained from the Korean National Environmental Health Survey (2012–2014). NAFLD was defined using the hepatic steatosis index (HSI). Blood mercury levels were log-transformed and divided into quartiles based on a weighted sample distribution. The association between blood mercury levels and NAFLD was analyzed using a multivariate logistic analysis after body mass index stratification. The geometric mean of blood mercury in the overweight group was significantly higher than that of the non-obese group (p < 0.001). The weighted frequencies of patients with NAFLD based on the HSI were 3.0–7.2% for the non-obese subjects and 52.3–63.2% for the overweight subjects. In the multivariate analysis, blood mercury levels were positively associated with NAFLD for both the overweight and non-obese groups (all p for trend < 0.001). Increased blood mercury levels are closely associated with NAFLD. In particular, mercury could be a risk factor for NAFLD in the non-obese population. © 2021 by the authors. Licensee MDPI, Basel, Switzerland. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI AG | - |
dc.title | Association between blood mercury levels and non-alcoholic fatty liver disease in non-obese populations: The korean national environmental health survey (konehs) 2012–2014 | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/ijerph18126412 | - |
dc.identifier.bibliographicCitation | International Journal of Environmental Research and Public Health, v.18, no.12 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000666691400001 | - |
dc.identifier.scopusid | 2-s2.0-85107784599 | - |
dc.citation.number | 12 | - |
dc.citation.title | International Journal of Environmental Research and Public Health | - |
dc.citation.volume | 18 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | Hepatic steatosis index | - |
dc.subject.keywordAuthor | Korean National Environmental Health Survey | - |
dc.subject.keywordAuthor | Mercury | - |
dc.subject.keywordAuthor | Non-alcoholic fatty liver disease | - |
dc.subject.keywordAuthor | Non-obese | - |
dc.subject.keywordPlus | blood | - |
dc.subject.keywordPlus | digestive system disorder | - |
dc.subject.keywordPlus | health survey | - |
dc.subject.keywordPlus | mercury (element) | - |
dc.subject.keywordPlus | multivariate analysis | - |
dc.subject.keywordPlus | risk factor | - |
dc.subject.keywordPlus | Korea | - |
dc.relation.journalResearchArea | Environmental Sciences & Ecology | - |
dc.relation.journalResearchArea | Public, Environmental & Occupational Health | - |
dc.relation.journalWebOfScienceCategory | Environmental Sciences | - |
dc.relation.journalWebOfScienceCategory | Public, Environmental & Occupational Health | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
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