Photoinduced cleavage by a rhodium complex at G center dot U mismatches and exposed guanines in large and small RNAs
DC Field | Value | Language |
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dc.contributor.author | Chow, Christine S. | - |
dc.contributor.author | Cunningham, Philip R. | - |
dc.contributor.author | Lee, Kangseok | - |
dc.contributor.author | Meroueh, May | - |
dc.contributor.author | SantaLucia, John | - |
dc.contributor.author | Varma, Shikha | - |
dc.date.accessioned | 2022-01-13T02:42:20Z | - |
dc.date.available | 2022-01-13T02:42:20Z | - |
dc.date.issued | 2002-09 | - |
dc.identifier.issn | 0300-9084 | - |
dc.identifier.issn | 1638-6183 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/53432 | - |
dc.description.abstract | Photoinduced cleavage reactions by the rhodium complex tris(4,7-diphenyl-1,10-phenanthroline)rhodium(III) {Rh(DIP)(3)(3+)} with three RNA hairpins, r(GGGGU UCGCUC CACCA) (16,nucleotide, tetraloop(Al2)), r(GGGGCUAUAGCUCUAGCUC CACCA) (24 nucleotide, microhelix(Ala)), and r(GGCGGUUAGAUAUCGCC) (17 nucleotide, 790 loop), and full-length (1542 nucleotide) 16S rRNA from Escherichia coli were investigated. The cleavage reactions were monitored by gel electrophoresis and the sites of cleavage by Rh(DIP)(3)(3+) were determined by comparisons with chemical or enzymatic sequencing reactions. In general, RNA backbone scission by the metal complex was induced at G-U mismatches and at exposed G residues. The cleavage activity was observed on the three small RNA hairpins as well as on the isolated 1542-nucleotide ribosomal RNA. (C) 2002 Societe francaise de biochimie et biologie moleculaire/Editions scientifiques et medicales Elsevier SAS. All rights reserved. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER FRANCE-EDITIONS SCIENTIFIQUES MEDICALES ELSEVIER | - |
dc.title | Photoinduced cleavage by a rhodium complex at G center dot U mismatches and exposed guanines in large and small RNAs | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/S0300-9084(02)01403-7 | - |
dc.identifier.bibliographicCitation | BIOCHIMIE, v.84, no.9, pp 859 - 868 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000179898000003 | - |
dc.identifier.scopusid | 2-s2.0-0036761232 | - |
dc.citation.endPage | 868 | - |
dc.citation.number | 9 | - |
dc.citation.startPage | 859 | - |
dc.citation.title | BIOCHIMIE | - |
dc.citation.volume | 84 | - |
dc.type.docType | Article | - |
dc.publisher.location | 프랑스 | - |
dc.subject.keywordAuthor | rhodium | - |
dc.subject.keywordAuthor | hairpin | - |
dc.subject.keywordAuthor | cleavage | - |
dc.subject.keywordAuthor | chemical probing | - |
dc.subject.keywordAuthor | 16S rRNA | - |
dc.subject.keywordPlus | RESPONSIVE ELEMENT RNA | - |
dc.subject.keywordPlus | TRANSITION-METAL COMPLEXES | - |
dc.subject.keywordPlus | RIBOSOMAL-RNA | - |
dc.subject.keywordPlus | WOBBLE PAIR | - |
dc.subject.keywordPlus | BASE-PAIRS | - |
dc.subject.keywordPlus | RECOGNITION | - |
dc.subject.keywordPlus | AMINOACYLATION | - |
dc.subject.keywordPlus | PHOTOCLEAVAGE | - |
dc.subject.keywordPlus | RESOLUTION | - |
dc.subject.keywordPlus | STABILITY | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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