Strong Correlation of Renal Function with Choroidal Thickness in Patients with Type 2 Diabetes: Retrospective Cross-Sectional Study
DC Field | Value | Language |
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dc.contributor.author | Choi, Min Gyu | - |
dc.contributor.author | Kim, Jee Taek | - |
dc.date.accessioned | 2022-01-13T06:43:13Z | - |
dc.date.available | 2022-01-13T06:43:13Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/53500 | - |
dc.description.abstract | The purpose of this study was to analyze the correlation between renal function and subfoveal choroidal thickness (SFChT) in treatment-naive proliferative diabetic retinopathy (PDR) patients. This study included 85 eyes of 52 treatment-naive PDR patients who underwent kidney function testing and urinalysis and 42 eyes of 33 age-matched controls. Treatment-naive eyes with PDR were categorized into pachychoroid and leptochoroid groups based on the SFChT of the control group. Kidney function profiles were compared between pachychoroid and leptochoroid groups; the relationship between kidney function profile and SFChT was evaluated using regression analysis. Compared with the pachychoroid group, the leptochoroid group had significantly higher serum creatinine (p= 0.026), cystatin C (p= 0.004), and phosphorus (p< 0.001) levels and a lower estimated glomerular filtration rate (eGFR) (p< 0.001). Multivariate linear regression analyses showed that SFChT was positively correlated with eGFR (Cystatin C) (p= 0.007) and negatively correlated with serum phosphorus (p= 0.001). SFChT of patients with eGFR < 30 mL/min/1.73 m(2)and serum phosphorus level >= 4.0 mg/dL was less than that of patients with higher eGFR and lower serum phosphorus level. The choroidal thickness of treatment-naive PDR patients is closely affected by renal function. Kidney function test should be considered if SFChT of patients with treatment-naive PDR is reduced. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Strong Correlation of Renal Function with Choroidal Thickness in Patients with Type 2 Diabetes: Retrospective Cross-Sectional Study | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/jcm9072171 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL MEDICINE, v.9, no.7, pp 1 - 12 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000554129000001 | - |
dc.identifier.scopusid | 2-s2.0-85114281584 | - |
dc.citation.endPage | 12 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1 | - |
dc.citation.title | JOURNAL OF CLINICAL MEDICINE | - |
dc.citation.volume | 9 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | diabetes complications | - |
dc.subject.keywordAuthor | diabetes mellitus | - |
dc.subject.keywordAuthor | diabetic retinopathy | - |
dc.subject.keywordAuthor | diabetic nephropathies | - |
dc.subject.keywordAuthor | choroidal thickness | - |
dc.subject.keywordAuthor | optical coherence tomography | - |
dc.subject.keywordPlus | CHRONIC KIDNEY-DISEASE | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | RETINOPATHY | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | MELLITUS | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
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