Molecular cytogenetic analysis of sperm from infertile males undergoing intracytoplasmic sperm injection.

Abstract

The successful implementation of intracytoplasmic sperm injection (ICSI) has provided a unique means to allow couples suffering from severe male infertility to achieve their reproductive goals. If the infertile man has a germ cell in the ejaculate or retrievable from the reproductive tract, ICSI can be carried out with remarkable fertilization results. However, despite the great therapeutic advantages of the technique, ICSI provides solutions to clinicians often in the absence of an etiologic or pathophysiologic diagnosis.