A Systematic Study on MR Contrast Agents for Constructing Specific Relaxation Times

Abstract

The water proton relaxation rates increase linearly with concentrations of contrast agents, and could be expressed as a function of the concentrations. In this paper, we have investigated MR properties of two different contrast agents, GdCl3 and CoCl2. Relaxivity coefficients were calculated from individual contrast agent solutions, and used for predicting relaxation rates at mixtures of two contrast agents. From the experimental results, we have discussed the feasibility of constructing water solutions with the desired relaxation times using specific mixtures of contrast agents.