Quantitative ultrasound radiofrequency data analysis for the assessment of hepatic steatosis using the controlled attenuation parameter as a reference standard
DC Field | Value | Language |
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dc.contributor.author | Jeon, Sun Kyung | - |
dc.contributor.author | Joo, Ijin | - |
dc.contributor.author | Kim, So Yeon | - |
dc.contributor.author | Jang, Jong Keon | - |
dc.contributor.author | Park, Juil | - |
dc.contributor.author | Park, Hee Sun | - |
dc.contributor.author | Lee, Eun Sun | - |
dc.contributor.author | Lee, Jeong Min | - |
dc.date.accessioned | 2022-01-24T00:40:14Z | - |
dc.date.available | 2022-01-24T00:40:14Z | - |
dc.date.issued | 2021-01 | - |
dc.identifier.issn | 2288-5919 | - |
dc.identifier.issn | 2288-5943 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/54111 | - |
dc.description.abstract | Purpose: This study was aimed to investigate the value of quantitative ultrasound (US) parameters from radiofrequency (RF) data analysis for assessing hepatic steatosis, using controlled attenuation parameter (CAP)-based steatosis grades as the reference standard. Methods: We analyzed 243 participants with both B-mode liver US with RF data acquisition and CAP measurements. On B-mode US images, hepatic steatosis was visually scored (0/1/2/3, none/mild/moderate/severe), and the hepatorenal index (HRI) was calculated. From the RF data analysis, the tissue scatter-distribution imaging parameter (TSI-p) and tissue attenuation imaging parameter (TAI-p) of the liver parenchyma were measured. US parameters were correlated with CAP-based steatosis grades (S0/1/2/3, none/mild/moderate/severe) and their diagnostic performance was evaluated using receiver operating characteristic (ROC) curve analysis. Multivariate linear regression analysis was performed to identify determinants of TSI-p and TAI-p. Results: Participants were classified as having S0 (n=152), S1 (n=54), S2 (n=14), and S3 (n=23) on CAP measurements. TSI-p and TAI-p were significantly correlated with steatosis grades (rho =0.593 and rho=-0.617, P<0.001 for both). For predicting >= S1, >= S2, and S3, the areas under the ROC curves (AUCs) of TSI-p were 0.827/0.914/0.917; TAI-p, 0.844/0.914/0.909; visual scores, 0.659/0.778/0.794; and HRI, 0.629/0.751/0.759, respectively. TSI-p and TAI-p had significantly higher AUCs than did visual scores or HRI for =S1 or =S2 (P=0.003). In the multivariate analysis, the transient elastography-based fibrosis grade (P=0.034) and steatosis grade (P< 0.001) were independent determinants of TSI-p, while steatosis grade (P<0.001) was an independent determinant of TAI-p. Conclusion: TSI-p and TAI-p derived from US RF data may be useful for detecting hepatic steatosis and assessing its severity. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC ULTRASOUND MEDICINE | - |
dc.title | Quantitative ultrasound radiofrequency data analysis for the assessment of hepatic steatosis using the controlled attenuation parameter as a reference standard | - |
dc.type | Article | - |
dc.identifier.doi | 10.14366/usg.20042 | - |
dc.identifier.bibliographicCitation | ULTRASONOGRAPHY, v.40, no.1, pp 136 - 146 | - |
dc.identifier.kciid | ART002669451 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000602774600014 | - |
dc.identifier.scopusid | 2-s2.0-85097185063 | - |
dc.citation.endPage | 146 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 136 | - |
dc.citation.title | ULTRASONOGRAPHY | - |
dc.citation.volume | 40 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Ultrasonography | - |
dc.subject.keywordAuthor | Liver | - |
dc.subject.keywordAuthor | Fatty liver | - |
dc.subject.keywordPlus | FATTY LIVER | - |
dc.subject.keywordPlus | TRANSIENT ELASTOGRAPHY | - |
dc.subject.keywordPlus | HEPATORENAL INDEX | - |
dc.subject.keywordPlus | MR SPECTROSCOPY | - |
dc.subject.keywordPlus | FIBROSIS | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | QUANTIFICATION | - |
dc.subject.keywordPlus | DIAGNOSIS | - |
dc.subject.keywordPlus | ACCURACY | - |
dc.subject.keywordPlus | VALIDITY | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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