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A microfluidic culture system for analysis of neurotoxicity of oligomeric assemblies of amyloid beta proteins
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Choi, Y.J. | - |
| dc.contributor.author | Chae, S. | - |
| dc.contributor.author | Kim, J.H. | - |
| dc.contributor.author | Park, J.Y. | - |
| dc.contributor.author | Lee, S.-H. | - |
| dc.date.accessioned | 2022-01-24T03:43:19Z | - |
| dc.date.available | 2022-01-24T03:43:19Z | - |
| dc.date.issued | 2012-11 | - |
| dc.identifier.issn | 0000-0000 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/54190 | - |
| dc.description.abstract | In this paper, we introduce a microfluidic system to analyze the effect of oligomeric assemblies of amyloid beta on neurons quantitatively with well-organized in vivo-like microenvironment. By generating extremely slow flow rate and gradient of oligomeric assemblies of amyloid beta, our microfluidic platform simulates the regulated intramembrane proteolysis (RIP), a convergence physiological mechanism. | - |
| dc.format.extent | 3 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | Chemical and Biological Microsystems Society | - |
| dc.title | A microfluidic culture system for analysis of neurotoxicity of oligomeric assemblies of amyloid beta proteins | - |
| dc.type | Article | - |
| dc.identifier.bibliographicCitation | Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012, pp 902 - 904 | - |
| dc.description.isOpenAccess | N | - |
| dc.identifier.scopusid | 2-s2.0-84901799009 | - |
| dc.citation.endPage | 904 | - |
| dc.citation.startPage | 902 | - |
| dc.citation.title | Proceedings of the 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2012 | - |
| dc.type.docType | Conference Paper | - |
| dc.subject.keywordAuthor | Microfluidic gradient chip | - |
| dc.subject.keywordAuthor | Oligomeric assemblies of amyloid beta | - |
| dc.subject.keywordPlus | Glycoproteins | - |
| dc.subject.keywordPlus | Microfluidics | - |
| dc.subject.keywordPlus | Oligomers | - |
| dc.subject.keywordPlus | Amyloid betas | - |
| dc.subject.keywordPlus | Culture systems | - |
| dc.subject.keywordPlus | Intramembrane proteolysis | - |
| dc.subject.keywordPlus | Micro fluidic system | - |
| dc.subject.keywordPlus | Microenvironments | - |
| dc.subject.keywordPlus | Microfluidic platforms | - |
| dc.subject.keywordPlus | Neurotoxicity | - |
| dc.subject.keywordPlus | Physiological mechanisms | - |
| dc.subject.keywordPlus | Proteins | - |
| dc.description.journalRegisteredClass | scopus | - |
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