Time-shifted multi-tracking of shear waves for the characterization of scleral biomechanics

Abstract

The biomechanics of the sclera can play a critical role in glaucoma diagnosis and monitoring new treatment methods. Previous studies have used strain elastography and investigated the relationship between scleral stiffness and intraocular pressure. However, applying shear wave elastography (SWE) to scleral tissue is challenging because sclera (100-1000 kPa) is significantly stiffer than normal soft tissue (10-100 kPa). We introduce a time-shifted multi-tracking approach capable of measuring the propagation of fast shear waves in stiff tissues, such as the sclera. © 2017 IEEE.