스테로이드 치료 후 회복기의 규칙적인 운동이 어린 쥐의 스테로이드 유발성 위축 Type II 근육에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최명애 | - |
dc.contributor.author | 신기수 | - |
dc.contributor.author | 안경주 | - |
dc.contributor.author | 최정안 | - |
dc.contributor.author | 이윤경 | - |
dc.date.accessioned | 2022-04-11T05:40:17Z | - |
dc.date.available | 2022-04-11T05:40:17Z | - |
dc.date.issued | 2002-06 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/56036 | - |
dc.description.abstract | -Effect of Regular Exercise during Recovery Period Following Steroid Treatment on the Atrophied Type II Muscles Induced by Steroid in Young Rats Purpose: This study was conducted to determine whether low intensity regular exercise following dexamethasone treatment could attenuate steroid-induced muscle atrophy. Method: 36 Wistar-rats(90-110g) were divided into six groups: control group(C), dexamethasone treatment group(D), sedentary group after normal sedentary period(C+S), sedentary group after dexamethasone treatment period(D+S), exercise group after normal sedentary period(C+E), and excercise group after dexamethasone treatment period(D+E). D, D+S, and D+E groups received dexamethasone injection(5mg/Kg) for seven days whereas C, C+S, and C+E groups received normal saline injection. Both C+E and D+E groups ran on a treadmill for 60 minutes/day(20minutes/4hours) at 15m/min and a 10°grade for seven recovery days. Result: Post-weight(body weight before muscle dissection) of D group significantly decreased by 16.03%, and that of D+E group significantly increased by 15.51% compared with pre-weight(body weight before steroid treatment). TypeⅡ muscle(plantaris and gastrocnemius) weights of D group were significantly lower than those of C group. Myofibrillar protein contents of typeⅡ muscles of D group tended to decrease comparing with C group. In D+E groups, body weights and relative weights of typeⅡ muscles(muscle weight(㎎)/post-weight(g)) tended to increase comparing with D+S group. Conclusion: It is suggested that steroid- induced muscle atrophy can be ameliorated through low intensity regular exercise after dexamethasone treatment. | - |
dc.format.extent | 10 | - |
dc.publisher | 한국간호과학회 | - |
dc.title | 스테로이드 치료 후 회복기의 규칙적인 운동이 어린 쥐의 스테로이드 유발성 위축 Type II 근육에 미치는 영향 | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Journal of Korean Academy of Nursing, v.32, no.4, pp 550 - 559 | - |
dc.identifier.kciid | ART000899029 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 559 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 550 | - |
dc.citation.title | Journal of Korean Academy of Nursing | - |
dc.citation.volume | 32 | - |
dc.subject.keywordAuthor | Exercise | - |
dc.subject.keywordAuthor | Steroid | - |
dc.subject.keywordAuthor | Fast-twitch muscle fibers | - |
dc.subject.keywordAuthor | Exercise | - |
dc.subject.keywordAuthor | Steroid | - |
dc.subject.keywordAuthor | Fast-twitch muscle fibers | - |
dc.description.journalRegisteredClass | kci | - |
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