Is gender still a predisposing factor in contrast-media associated adverse drug reactions? A systematic review and meta-analysis of randomized trials and observational studies
DC Field | Value | Language |
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dc.contributor.author | Lee, Heeyoung | - |
dc.contributor.author | Song, Seungyeon | - |
dc.contributor.author | Oh, Yun-Kyoung | - |
dc.contributor.author | Kang, WonKu | - |
dc.contributor.author | Kim, Eunyoung | - |
dc.date.accessioned | 2022-04-11T06:40:31Z | - |
dc.date.available | 2022-04-11T06:40:31Z | - |
dc.date.issued | 2017-04 | - |
dc.identifier.issn | 0720-048X | - |
dc.identifier.issn | 1872-7727 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/56065 | - |
dc.description.abstract | Objective: To evaluate the role of gender as a risk factor for developing contrast media-associated adverse drug reactions (CM-ADRs) by comparing the incidence of CM-ADR between male and female patients according to study design, ADR type, and computed tomography (CT) examination. Material and methods: We systematically searched three electronic databases for eligible studies. In the studies included (n = 18), we assessed effect estimates of the relative incidence of CM-ADR, analysed by experimental design, ADR type and CT examination. This was calculated by using a random effects model if clinical conditions showed heterogeneity; otherwise, a fixed effects model was used. Results: We identified 10,776 patients administered CM. According to the designs, studies were classified into randomised controlled trials (RCTs) and observational studies. Results were as follows: risk ratio (RR) = 1.07 (95% confidence interval (CI): 0.79-1.46, P = 0.66) for RCTs, and RR = 0.77 (95% CI: 0.58-1.04, P = 0.09) for observational studies. The results of analysis according to ADR type and for undergoing CT demonstrated that the incidence of CM-ADR did not differ between males and females. Conclusions: We found no significant difference in the incidence of CM-ADRs between male and female patients according to study design, ADR type, or CT examination. Future studies to determine why gender has shown different roles as a risk factor between CM-ADRs and non-CM ADRs are needed. (C) 2017 Elsevier B.V. All rights reserved. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER IRELAND LTD | - |
dc.title | Is gender still a predisposing factor in contrast-media associated adverse drug reactions? A systematic review and meta-analysis of randomized trials and observational studies | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.ejrad.2017.01.015 | - |
dc.identifier.bibliographicCitation | EUROPEAN JOURNAL OF RADIOLOGY, v.89, pp 81 - 89 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000401094900013 | - |
dc.identifier.scopusid | 2-s2.0-85011604808 | - |
dc.citation.endPage | 89 | - |
dc.citation.startPage | 81 | - |
dc.citation.title | EUROPEAN JOURNAL OF RADIOLOGY | - |
dc.citation.volume | 89 | - |
dc.type.docType | Article | - |
dc.publisher.location | 아일랜드 | - |
dc.subject.keywordAuthor | Contrast media | - |
dc.subject.keywordAuthor | Adverse drug reaction | - |
dc.subject.keywordAuthor | Gender | - |
dc.subject.keywordAuthor | Systematic review | - |
dc.subject.keywordAuthor | Meta-analysis | - |
dc.subject.keywordPlus | MEDIUM-INDUCED NEPHROPATHY | - |
dc.subject.keywordPlus | ACUTE KIDNEY INJURY | - |
dc.subject.keywordPlus | RISK-FACTORS | - |
dc.subject.keywordPlus | CORONARY-ANGIOGRAPHY | - |
dc.subject.keywordPlus | ELDERLY-PATIENTS | - |
dc.subject.keywordPlus | HIGH-OSMOLALITY | - |
dc.subject.keywordPlus | CT ANGIOGRAPHY | - |
dc.subject.keywordPlus | SAFETY PROFILE | - |
dc.subject.keywordPlus | RENAL-FUNCTION | - |
dc.subject.keywordPlus | FEMALE GENDER | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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