Total synthesis of 2′,4′,6′-trimethoxy-3′,5′-dimethylchalcone derivatives
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Park, Rae Yeon | - |
dc.contributor.author | Lee, Hana | - |
dc.contributor.author | Park, Kwangyong | - |
dc.date.accessioned | 2022-04-25T07:40:19Z | - |
dc.date.available | 2022-04-25T07:40:19Z | - |
dc.date.issued | 2022-05 | - |
dc.identifier.issn | 0253-2964 | - |
dc.identifier.issn | 1229-5949 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/56732 | - |
dc.description.abstract | 2′,4′-Dihydroxy-6′-methoxy-3′,5′-dimethylchalcone (DMC), which is isolated from plants, has recently attracted much attention due to its beneficial pharmacological effects. The preparation of twelve 2′,4′,6′-trimethoxy-3′,5′-dimethylchalcone (DMDMC) derivatives, which are dimethylated-derivatives of DMC, is reported herein for the first time. Our synthetic method allowed the efficient construction of the DMDMC derivatives from phloroglucinol in 37.8%–46.5% overall yields. This promising approach would be advantageous for the production of many different DMDMC derivatives in a short period of time. © 2022 Korean Chemical Society, Seoul & Wiley-VCH GmbH | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | John Wiley and Sons Inc | - |
dc.title | Total synthesis of 2′,4′,6′-trimethoxy-3′,5′-dimethylchalcone derivatives | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/bkcs.12515 | - |
dc.identifier.bibliographicCitation | Bulletin of the Korean Chemical Society, v.43, no.5, pp 731 - 738 | - |
dc.identifier.kciid | ART002840424 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000765235500001 | - |
dc.identifier.scopusid | 2-s2.0-85125671781 | - |
dc.citation.endPage | 738 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 731 | - |
dc.citation.title | Bulletin of the Korean Chemical Society | - |
dc.citation.volume | 43 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | 2′,4′,6′-trimethoxy-3′,5′-dimethylchalcone | - |
dc.subject.keywordAuthor | antidiabetic compounds | - |
dc.subject.keywordAuthor | chalcone derivatives | - |
dc.subject.keywordAuthor | dimethyl cardamonin | - |
dc.subject.keywordAuthor | total synthesis | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | INDUCTION | - |
dc.subject.keywordPlus | CHALCONE | - |
dc.subject.keywordPlus | 2',4'-DIHYDROXY-6'-METHOXY-3',5'-DIMETHYLCHALCONE | - |
dc.subject.keywordPlus | APOPTOSIS | - |
dc.subject.keywordPlus | CELLS | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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