In situ monitoring of antibiotic susceptibility of bacterial biofilms in a microfluidic device
DC Field | Value | Language |
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dc.contributor.author | Kim, Keun Pil | - |
dc.contributor.author | Kim, Yun-Gon | - |
dc.contributor.author | Choi, Chang-Hyung | - |
dc.contributor.author | Kim, Hye-Eun | - |
dc.contributor.author | Lee, Sang-Ho | - |
dc.contributor.author | Chang, Woo-Suk | - |
dc.contributor.author | Lee, Chang-Soo | - |
dc.date.accessioned | 2022-05-09T08:40:17Z | - |
dc.date.available | 2022-05-09T08:40:17Z | - |
dc.date.issued | 2010-12 | - |
dc.identifier.issn | 1473-0197 | - |
dc.identifier.issn | 1473-0189 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/57443 | - |
dc.description.abstract | Antibiotic resistance of biofilms is a growing public health concern due to overuse and improper use of antibiotics. Thus, determining an effective minimal concentration of antibiotics to eradicate bacterial biofilms is crucial. Here we present a simple, novel one-pot assay for the analysis of antibiotic susceptibility of bacterial biofilms using a microfluidics system where continuous concentration gradients of antibiotics are generated. The results of minimal biofilm eradication concentration (MBEC) clearly confirm that the concentration required to eradicate biofilm-grown Pseudomonas aeruginosa is higher than the minimal inhibitory concentration (MIC) that has been widely used to determine the lowest concentration of antibiotics against planktonically grown bacteria. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | In situ monitoring of antibiotic susceptibility of bacterial biofilms in a microfluidic device | - |
dc.type | Article | - |
dc.identifier.doi | 10.1039/c0lc00154f | - |
dc.identifier.bibliographicCitation | LAB ON A CHIP, v.10, no.23, pp 3296 - 3299 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000284068200016 | - |
dc.identifier.scopusid | 2-s2.0-78149377810 | - |
dc.citation.endPage | 3299 | - |
dc.citation.number | 23 | - |
dc.citation.startPage | 3296 | - |
dc.citation.title | LAB ON A CHIP | - |
dc.citation.volume | 10 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordPlus | PSEUDOMONAS-AERUGINOSA | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | CHEMOTAXIS | - |
dc.subject.keywordPlus | GRADIENTS | - |
dc.subject.keywordPlus | MODEL | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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