Microtubes with Rectangular Cross-Section by Self-Assembly of a Short beta-Peptide Foldamer
- Authors
- Kim, Jangbae; Kwon, Sunbum; Kim, Su Hyun; Lee, Chung-Kyung; Lee, Joon-Hwa; Cho, Sung June; Lee, Hee-Seung; Ihee, Hyotcherl
- Issue Date
- Dec-2012
- Publisher
- AMER CHEMICAL SOC
- Citation
- JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, v.134, no.51, pp 20573 - 20576
- Pages
- 4
- Journal Title
- JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Volume
- 134
- Number
- 51
- Start Page
- 20573
- End Page
- 20576
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/57635
- DOI
- 10.1021/ja3088482
- ISSN
- 0002-7863
1520-5126
- Abstract
- In nature, complex and well-defined structures are constructed by the self-assembly of biomolecules. It has been shown that beta-peptide foldamers can mimic natural peptides and self-assemble into three-dimensional molecular architectures thanks to their rigid and predictable helical conformation in solution. Using shorter foldamers, which can be prepared more easily than longer ones, to form such architectures is highly desirable, but shorter foldamers have been overlooked due to the seemingly inferior number of intramolecular hydrogen bonds to stabilize a folded state in solution. Here we report that a beta-peptide tetramer, although it lacks full helical propensity in solution, does self-assemble to form well-defined microtubes with rectangular cross-section by evaporation-induced self-assembly.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Natural Sciences > Department of Chemistry > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/57635)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.