Elastomeric polypentapeptides cross-linked into matrixes and fibers
DC Field | Value | Language |
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dc.contributor.author | Lee, Jonghwi | - |
dc.contributor.author | Macosko, Christopher W. | - |
dc.contributor.author | Urry, Dan W. | - |
dc.date.accessioned | 2022-05-19T10:40:39Z | - |
dc.date.available | 2022-05-19T10:40:39Z | - |
dc.date.issued | 2001-03 | - |
dc.identifier.issn | 1525-7797 | - |
dc.identifier.issn | 1526-4602 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/57838 | - |
dc.description.abstract | Microbially prepared polypentapeptides were cross-linked by two chemical methods. In one chemical approach, (GVGIP)(260) where G = glycine, V = valine, I = isoleucine, and P = proline with no functional groups in its side chains, was cross-linked using dicumyl peroxide, and reaction conditions were systematically examined. Successful cross-linking was obtained even under Severe conditions for proteins, i.e., 3 h at 120 degreesC, without having significant side reactions. In the second chemical approach, two separate polymers, (GVGVP GVGVP GXGVP GVGVP GVGVP GVGVP)(n) where X is either E (the carboxylic, acid containing glutamic acid residue) or K (the lysine residue with an epsilon -amino function), were mixed and cross-linked using a carbodiimde reagent. The reaction temperature was found to affect the equilibrium swelling behavior of the resulting cross-linked hydrogels. In hydrogels cross-linked at a temperature above their hydrophobic folding and assembling transition temperature, 3D continuous filamentous microstructures were observed. Chemically cross-linked hydrogel fibers were also prepared and their anisotropy in swelling was confirmed. Uniaxial tensile moduli and equilibrium weight swelling ratios of the chemically cross-linked samples were compared to those of (GVGVP)(251) and (GVGIP)(260), gamma -irradiation cross-linked at different Mrad doses. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | AMER CHEMICAL SOC | - |
dc.title | Elastomeric polypentapeptides cross-linked into matrixes and fibers | - |
dc.type | Article | - |
dc.identifier.doi | 10.1021/bm0000900 | - |
dc.identifier.bibliographicCitation | BIOMACROMOLECULES, v.2, no.1, pp 170 - 179 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000168755800023 | - |
dc.citation.endPage | 179 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 170 | - |
dc.citation.title | BIOMACROMOLECULES | - |
dc.citation.volume | 2 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordPlus | INVERSE TEMPERATURE TRANSITION | - |
dc.subject.keywordPlus | PROTEIN-BASED POLYMERS | - |
dc.subject.keywordPlus | PHASE-TRANSITION | - |
dc.subject.keywordPlus | N-ISOPROPYLACRYLAMIDE | - |
dc.subject.keywordPlus | SWELLING BEHAVIOR | - |
dc.subject.keywordPlus | ELASTIN | - |
dc.subject.keywordPlus | HYDROGELS | - |
dc.subject.keywordPlus | POLYPEPTIDES | - |
dc.subject.keywordPlus | LINKING | - |
dc.subject.keywordPlus | ENERGY | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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