HPLC-UV를 이용한 중마황의 (+)-Pseudoephedrine과 (-)-Ephedrine의 동시분석법 개발
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정비랑 | - |
dc.contributor.author | 윤유식 | - |
dc.contributor.author | 신순식 | - |
dc.contributor.author | 권용수 | - |
dc.contributor.author | 양희정 | - |
dc.date.available | 2019-03-08T11:38:07Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 0253-3073 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/6087 | - |
dc.description.abstract | Ephedra alkaloids, (-)-ephedrine, (+)-pseudoephedrine, (-)-N-methylephedrine, (+)-N-methylpseudoephedrine, (-)- norephedrine and (+)-norpseudoephedrine, from ephedra herb are sympathomimetic agonists causing an increase of metabolism, blood pressure and perspiration. In this study, we developed the validation method of (+)-pseudoephedrine and (-)-ephedrine, two major ephedra alkaloids in Ephedra spp., by high-performance liquid chromatography-ultraviolet spectrometer (HPLC-UV). HPLC analysis was performed using a HECTOR-M C18 column operating at 35°C, and UV detection at 215nm. The mobile phase used a gradient flow with 25 mM SDS in water (A) and acetonitrile (B). © 2017, Korean Society of Pharmacognosy. All rights reserved. | - |
dc.format.extent | 4 | - |
dc.language | 중국어 | - |
dc.language.iso | CHI | - |
dc.publisher | Korean Society of Pharmacognosy | - |
dc.title | HPLC-UV를 이용한 중마황의 (+)-Pseudoephedrine과 (-)-Ephedrine의 동시분석법 개발 | - |
dc.title.alternative | Simultaneous Determination of (+)-Pseudoephedrine and (-)-Ephedrine in Ephedra intermedia by HPLC-UV | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Korean Journal of Pharmacognosy, v.48, no.1, pp 93 - 96 | - |
dc.identifier.kciid | ART002207898 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-85017202021 | - |
dc.citation.endPage | 96 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 93 | - |
dc.citation.title | Korean Journal of Pharmacognosy | - |
dc.citation.volume | 48 | - |
dc.identifier.url | https://scienceon.kisti.re.kr/srch/selectPORSrchArticle.do?cn=JAKO201714940711593&SITE=CLICK | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Ephedra intermedia | - |
dc.subject.keywordAuthor | Ephedrine | - |
dc.subject.keywordAuthor | HPLC analysis | - |
dc.subject.keywordAuthor | Method validation | - |
dc.subject.keywordAuthor | Pseudoephedrine | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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