한국형 양극성 장애 약물치료 알고리듬 2022: 혼재성 양상open accessKorean Medication Algorithm Project for Bipolar Disorder 2022: Mixed Features
- Authors
- 김원; 박원명; 우영섭; 정종현; 서정석; 추일한; 양찬모; 이정구; 심세훈; 윤보현; 박성용; 손인기; 김문두; 정명훈; 전덕인
- Issue Date
- May-2022
- Publisher
- 대한신경정신의학회
- Keywords
- Bipolar disorder; KMAP-BP 2022; Pharmacotherapy; Mixed features
- Citation
- 신경정신의학, v.61, no.2, pp 133 - 142
- Pages
- 10
- Journal Title
- 신경정신의학
- Volume
- 61
- Number
- 2
- Start Page
- 133
- End Page
- 142
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/61344
- DOI
- 10.4306/jknpa.2022.61.2.133
- ISSN
- 1015-4817
2289-0963
- Abstract
- Objectives Treatment guidelines or an algorithm can help clinicians implement better practices and clinical decisions. Therefore, the Korean Medication Algorithm Project for Bipolar Disorder 2022 (KMAP-BP 2022) was revised again through a consensus of expert opinion. The diagnosis and treatment of mixed features are not simple, and there are many things to discuss. We describe the preferences and recommendations from KMAP-BP 2022 for the treatment of mood episodes with mixed features.
Methods We revised the KMAP-BP 2018 questionnaire and conducted the survey with expert clinicians. Out of ninety-three members of the review committee, eighty-seven completed the survey. We analyzed the answers, discussed the data, and held a clinician hearing.
Results In first-step strategies for mixed features with more manic symptoms, a combination of a mood stabilizer and an atypical antipsychotic is the treatment of choice. Mood stabilizer monotherapy and atypical antipsychotic monotherapy are preferred strategies. For mixed features with more depressive symptoms, a combination of mood stabilizer and atypical antipsychotic, a combination of atypical antipsychotic and lamotrigine (LMT), atypical antipsychotic monotherapy, a combination of mood stabilizer and LMT, and mood stabilizer monotherapy are preferred. For mixed features with similar manic symptoms and depressive symptoms, a combination of mood stabilizer and atypical antipsychotic, atypical antipsychotic monotherapy, and mood stabilizer monotherapy are preferred.
Conclusion For mixed features, a combination of mood stabilizer and atypical antipsychotic is generally preferred, and LMT is preferred for depressive symptoms. Compared with KMAP-BP 2018, more diverse strategies and drugs are being attempted for the treatment of mixed features.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - ETC > 1. Journal Articles
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.