Analysis of the Efficacy of Universal Screening of Coronavirus Disease with Antigen-Detecting Rapid Diagnostic Tests at Point-or-Care Settings and Sharing the Experience of Admission Protocol—A Pilot Study
DC Field | Value | Language |
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dc.contributor.author | Park, J.Y. | - |
dc.contributor.author | Lee, J.H. | - |
dc.contributor.author | Cha, B.K. | - |
dc.contributor.author | Kim, B.-S. | - |
dc.contributor.author | Lee, H.-J. | - |
dc.contributor.author | Kim, G.H. | - |
dc.contributor.author | Kang, K.-T. | - |
dc.contributor.author | Lee, Y.-S. | - |
dc.contributor.author | Ahn, S.K. | - |
dc.contributor.author | Kim, S.H. | - |
dc.date.accessioned | 2023-03-08T08:42:03Z | - |
dc.date.available | 2023-03-08T08:42:03Z | - |
dc.date.issued | 2022-02 | - |
dc.identifier.issn | 2075-4426 | - |
dc.identifier.issn | 2075-4426 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/61659 | - |
dc.description.abstract | Aims: To introduce the admission protocol of a COVID-19 specialized hospital outlined by the government, including the assessment of reverse transcription polymerase chain reaction (RT-PCR), low dose chest computed tomography (CT) and antigen-detecting rapid diagnostic test (Ag-RDT) for patient screening. Materials and Methods: This was a retrospective cohort study of 646 patients who were admitted between December 2020, and February 2021, during the third wave of COVID-19 in Korea. Ag-RDT and RT-PCR were routinely performed on all patients who required admission, and low-dose chest CT was performed on high-risk patients with associated symptoms. Any patients with high-risk COVID-19 infection according to the Ag-RDT test were quarantined alone in a negative pressured room, and those with low-risk COVID-19 infection remained in the preemptive quarantine room with or without negative pressure. The diagnostic values of the Ag-RDT test and associated cycle threshold (Ct) values of the RT-PCR test were subsequently evaluated. Results: In terms of the diagnostic value, the Ag-RDT for COVID-19 had a sensitivity of 68.3%, specificity of 99.5%, positive predictive value (PPV) of 90.3%, and negative predictive value (NPV) of 97.9%. For the 355 symptomatic patients with low-dose chest CT, the diagnostic values of combined evaluations had a sensitivity of 90.2%, specificity of 99.0%, PPV of 86.1%, and NPV of 99.3%. The cut-off Ct value for positive Ag-RDT was ≤25.67 for the N gene (sensitivity: 89.3%, specificity: 100%), which was regarded as a high viable virus in cell culture. There were no patients or medical staff who had COVID-19 in the hospital. Conclusion: Appropriate patient care was possible by definitive triage of the area, according to the symptoms and using diagnostic tests. Screening protocols, including the Ag-RDT test and low-dose chest CT, could be helpful in emergency point-of-care settings. © 2022 by the authors. Licensee MDPI, Basel, Switzerland. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI | - |
dc.title | Analysis of the Efficacy of Universal Screening of Coronavirus Disease with Antigen-Detecting Rapid Diagnostic Tests at Point-or-Care Settings and Sharing the Experience of Admission Protocol—A Pilot Study | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/jpm12020319 | - |
dc.identifier.bibliographicCitation | Journal of Personalized Medicine, v.12, no.2 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000769711300001 | - |
dc.identifier.scopusid | 2-s2.0-85125361228 | - |
dc.citation.number | 2 | - |
dc.citation.title | Journal of Personalized Medicine | - |
dc.citation.volume | 12 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | COVID-19 | - |
dc.subject.keywordAuthor | Cross infection | - |
dc.subject.keywordAuthor | Infection control | - |
dc.subject.keywordAuthor | SARS-CoV-2 | - |
dc.relation.journalResearchArea | Health Care Sciences & Services | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Health Care Sciences & Services | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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