마카 품종별 조다당 획분의 대식세포 활성Macrophage Stimulating Activity of Crude Polysaccharide on Maca (Lepidium meyenii) Varieties
- Authors
- 신현영; 유광원; 김훈; 정은진
- Issue Date
- Feb-2022
- Publisher
- 한국식품영양학회
- Keywords
- maca (Lepidium meyenii); hot-water extract; crude polysaccharide; macrophage stimulating activity
- Citation
- 한국식품영양학회지, v.35, no.1, pp 7 - 15
- Pages
- 9
- Journal Title
- 한국식품영양학회지
- Volume
- 35
- Number
- 1
- Start Page
- 7
- End Page
- 15
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/61673
- DOI
- 10.9799/ksfan.2022.35.1.007
- ISSN
- 1225-4339
- Abstract
- Maca roots (Lepidium meyenii) are an important medicinal herb that have long been used by the Andes-indigenous peoples and South Americans. In Korea, recently, it has attracted attention as a health food material because of nutritional values and physiological activities. The purpose of this study was to investigate the industrial applicability of maca (red and golden varieties; R&G) as immunostimulating materials. In the macrophage stimulating assay using RAW 264.7 cells at 125~500 μg/mL of non-cytotoxicity doses, G-HW showed the most potent production of TNF-α, IL-6 and nitric oxide compared to red maca or the other extracts. The general component analysis results showed that all extracts comprised more than 90% neutral sugars with small amounts of uronic acid and protein. Meanwhile, component sugar analysis showed the difference in the content of uronic acids of cold- and hot-water extract. Additionally, the further fractionation of G-HW into crude polysaccharide (G-CP) greatly enhanced the macrophage stimulating activity, and G-CP contained macromolecules over 144 kDa, comprised mainly of glucose and galacturonic acid (51.0 and 34.9%).
In conclusion, crude polysaccharide from maca showed industrial applicability as immunostimulating material, and especially golden maca showed higher macrophage stimulating activity than red maca.
Key words: maca (Lepidium meyenii), hot-water extract, crude polysaccharide, macrophage stimulating activity
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Collections - College of Biotechnology & Natural Resource > Department of Systems Biotechnology > 1. Journal Articles
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