방광암에서 요로 마이크로바이옴의 임상적 의미open accessClinical Implications of Urinary Microbiome in Bladder Cancer
- Authors
- 심재헌; 국준희; 장인호; 손정민; 성신우; 지병훈
- Issue Date
- 2021
- Publisher
- 대한비뇨기종양학회
- Keywords
- Microbiome; Bladder cancer; Biomarker
- Citation
- 대한비뇨기종양학술지, v.19, no.2, pp 71 - 78
- Pages
- 8
- Journal Title
- 대한비뇨기종양학술지
- Volume
- 19
- Number
- 2
- Start Page
- 71
- End Page
- 78
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/62978
- DOI
- 10.22465/kjuo.2021.19.2.71
- ISSN
- 1598-8341
2233-5633
- Abstract
- Microbiomes are known to have a beneficial effect on human health by promoting the effective removal of improperly functioning immune cells and protecting the host from pathogen infection.
On the other hand, these microbiomes are also known as the causative agent of numerous malignant tumors. Until now, the bladder has been regarded as aseptic, but the concept of the “sterile bladder” has been changed with the discovery of living bacteria embedded in the bladder with the recent development of polymerase chain reaction and culture techniques. This paper referred to the relationship between microbiome and bladder cancer. Microbiome will be able to be seen as a non-invasive biomarker to predict the success rate of intravesical bacillus Calmette-Guerin instillation treatment in patients of bladder cancer.
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