Association between Inflammatory Biomarkers and Nutritional Status in Fatty Liver
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임희숙 | - |
dc.contributor.author | 최정윤 | - |
dc.contributor.author | 이보라 | - |
dc.contributor.author | 김상균 | - |
dc.contributor.author | 김영석 | - |
dc.contributor.author | 유정주 | - |
dc.date.accessioned | 2023-03-08T14:51:30Z | - |
dc.date.available | 2023-03-08T14:51:30Z | - |
dc.date.issued | 2020 | - |
dc.identifier.issn | 2287-3732 | - |
dc.identifier.issn | 2287-3740 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/63597 | - |
dc.description.abstract | The prevalence and progression of non-alcoholic fatty liver disease (NAFLD) is mediated via several factors correlating with hepatic necroinflammation (adipokines/cytokines). This study was performed to analyze the level of inflammatory markers according to the presence of NAFLD and to identify related nutritional factors. A total of 80 adults were classified into 2 groups (healthy and NAFLD), and their body composition, blood tests, and eating habits were evaluated. In addition, inflammatory markers (adiponectin, high-sensitivity C-reactive protein [CRP], and tumor necrosis factor-alpha [TNF-α]), nutrient intake status, and dietary quality were compared. The quality of diet was assessed according to the nutrient adequacy ratio and the mean adequacy ratio (MAR). The NAFLD group had a higher body mass index (p < 0.001) than the healthy group and also carried significantly higher CRP levels (p < 0.001) but lower adiponectin (p = 0.001). TNF-α levels increased significantly with fatty liver grade (p = 0.023). The NAFLD group showed significantly higher intake of energy, carbohydrates, iron, sodium, vitamin A and saturated fatty acids, but significantly lower intake of zinc and vitamin E than the healthy group. The MAR values were slightly higher in the NAFLD group but without any significant difference. The levels of adiponectin and vitamin E showed a significant inverse correlation (p < 0.05). Nutritional management of NAFLD patients is important, and the intake of antioxidant and anti-inflammatory nutrients such as zinc and vitamin E should be emphasized. | - |
dc.format.extent | 13 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국임상영양학회 | - |
dc.title | Association between Inflammatory Biomarkers and Nutritional Status in Fatty Liver | - |
dc.type | Article | - |
dc.identifier.doi | 10.7762/cnr.2020.9.3.182 | - |
dc.identifier.bibliographicCitation | Clinical Nutrition Research, v.9, no.3, pp 182 - 194 | - |
dc.identifier.kciid | ART002612074 | - |
dc.description.isOpenAccess | Y | - |
dc.citation.endPage | 194 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 182 | - |
dc.citation.title | Clinical Nutrition Research | - |
dc.citation.volume | 9 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Non-alcoholic fatty liver disease | - |
dc.subject.keywordAuthor | Adipokines | - |
dc.subject.keywordAuthor | Adiponectin | - |
dc.subject.keywordAuthor | Nutrients | - |
dc.subject.keywordAuthor | Vitamin E | - |
dc.description.journalRegisteredClass | kci | - |
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