Differences in Adverse Reactions Among Iodinated Contrast Media: Analysis of the KAERS Database
DC Field | Value | Language |
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dc.contributor.author | An, Jin | - |
dc.contributor.author | Jung, Heewon | - |
dc.contributor.author | Kwon, Oh Young | - |
dc.contributor.author | Kang, Yewon | - |
dc.contributor.author | Lee, Ji-Hyang | - |
dc.contributor.author | Won, Ha-Kyeong | - |
dc.contributor.author | Song, Woo-Jung | - |
dc.contributor.author | Kwon, Hyouk-Soo | - |
dc.contributor.author | Cho, You Sook | - |
dc.contributor.author | Moon, Hee-Bom | - |
dc.contributor.author | Kim, Tae-Bum | - |
dc.date.accessioned | 2023-03-08T14:59:28Z | - |
dc.date.available | 2023-03-08T14:59:28Z | - |
dc.date.issued | 2019-09 | - |
dc.identifier.issn | 2213-2198 | - |
dc.identifier.issn | 2213-2201 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/63719 | - |
dc.description.abstract | BACKGROUND: The various adverse drug reactions (ADRs) arise from different types of iodinated contrast media (ICM). OBJECTIVE: Thus, we investigated the occurrence rate and types of ADRs according to the total usage cases of the 7 most common ICM. METHODS: We retrospectively reviewed 74,242 causal ADRs caused by ICM from the Korea Adverse Event Reporting System database between January 2014 and December 2016. The 11,712,796 total usage cases that represent all administrations of ICM reported from individual medical institutions were received from the Health Insurance Review and Assessment Service. A proportionality test was used to examine the differences in the frequency ratio of causal ADRs to total usage cases. RESULTS: Immediate hypersensitivity (44,467 cases, 88.56%) occurred more frequently than delayed hypersensitivity (5,725 cases, 11.4%; P < .001). The overall occurrence rate of causal ADRs and serious ADRs considering total usage cases was 0.37% and 0.02%, respectively (P < .001). The ICM most commonly resulting in ADRs were iomeprol (0.7%) and iopromide (0.59%). The serious ADRs were most common for iomeprol (0.05%). When ADRs were classified according to the system organ class, "skin and appendages disorders" (47,065 cases, 63.4%) occurred most common. Iodixanol resulted in the highest frequency of "urinary system disorders." CONCLUSIONS: By comparison of the ADRs considering total usage cases, the incidence and classification of ADRs were different for each contrast medium. A prospective study is needed because the differences in these 7 major contrast media may assist in the selection of ICM tailored for each patient. (C) 2019 American Academy of Allergy, Asthma & Immunology. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER | - |
dc.title | Differences in Adverse Reactions Among Iodinated Contrast Media: Analysis of the KAERS Database | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jaip.2019.02.035 | - |
dc.identifier.bibliographicCitation | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE, v.7, no.7, pp 2205 - 2211 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000484456300017 | - |
dc.citation.endPage | 2211 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 2205 | - |
dc.citation.title | JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY-IN PRACTICE | - |
dc.citation.volume | 7 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | Contrast media | - |
dc.subject.keywordAuthor | Adverse drug reaction | - |
dc.subject.keywordAuthor | Hypersensitivity | - |
dc.subject.keywordAuthor | System organ class | - |
dc.subject.keywordAuthor | Computed tomography | - |
dc.subject.keywordPlus | RENAL SAFETY | - |
dc.subject.keywordPlus | OSMOLAR | - |
dc.subject.keywordPlus | FREQUENCY | - |
dc.subject.keywordPlus | EVENTS | - |
dc.subject.keywordPlus | AGENTS | - |
dc.subject.keywordPlus | RISK | - |
dc.relation.journalResearchArea | Allergy | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalWebOfScienceCategory | Allergy | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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