The reciprocal interaction between LV remodelling and allograft outcomes in kidney transplant recipients
DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Jung Nam | - |
dc.contributor.author | Kim, Young Hoon | - |
dc.contributor.author | Park, Jun-Bean | - |
dc.contributor.author | Hwang, Jin Ho | - |
dc.contributor.author | Yoo, Kyung Don | - |
dc.contributor.author | Park, Jae Yoon | - |
dc.contributor.author | Kim, Clara Tammy | - |
dc.contributor.author | Kim, Hack-Lyoung | - |
dc.contributor.author | Kim, Yong-Jin | - |
dc.contributor.author | Han, Duck-Jong | - |
dc.contributor.author | Lim, Chun Soo | - |
dc.contributor.author | Kim, Yon Su | - |
dc.contributor.author | Lee, Jung Pyo | - |
dc.date.accessioned | 2023-03-08T18:24:12Z | - |
dc.date.available | 2023-03-08T18:24:12Z | - |
dc.date.issued | 2015-11 | - |
dc.identifier.issn | 1355-6037 | - |
dc.identifier.issn | 1468-201X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/64440 | - |
dc.description.abstract | Objective This study aimed to investigate the incidence and related clinical factors of LV hypertrophy (LVH) regression after kidney transplantation and its effect on graft outcome. Methods Among the 3373 kidney transplant recipients who were enrolled in a multicentre cohort from 1997 to 2012, a total of 767 patients who underwent echocardiography before and after transplantation were included in this study followed for a median of 7.5 years. Results LVH regression steadily increased from 7.4% at 1 year to 35.4% at 5 years over the 5-year post-transplantation period. The probability of LVH regression decreased in the patients who received a kidney transplant due to end-stage renal disease of unknown aetiology (p=0.041) or who underwent pretransplant haemodialysis (p=0.020). The probability of LVH regression also decreased as the pretransplant LV mass index (p<0.001) and post-transplant systolic blood pressure increased (p=0.005). Conversely, LVH regression was significantly associated with the highest tertile of the pretransplant haemoglobin level (p=0.029). Furthermore, in the 5th year after transplantation, persistent LVH was independently associated with allograft failure (HR 1.95; 95% CI 1.14 to 3.33; p=0.015) and the LV mass index reliably predicted graft outcome. Conclusions LVH consistently regressed after kidney transplantation in most patients. Persistent LVH, low haemoglobin levels and elevated blood pressure were associated with an increased risk of allograft failure in kidney transplant recipients. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | BMJ PUBLISHING GROUP | - |
dc.title | The reciprocal interaction between LV remodelling and allograft outcomes in kidney transplant recipients | - |
dc.type | Article | - |
dc.identifier.doi | 10.1136/heartjnl-2015-308142 | - |
dc.identifier.bibliographicCitation | HEART, v.101, no.22, pp 1826 - 1833 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000363808800012 | - |
dc.identifier.scopusid | 2-s2.0-84948457926 | - |
dc.citation.endPage | 1833 | - |
dc.citation.number | 22 | - |
dc.citation.startPage | 1826 | - |
dc.citation.title | HEART | - |
dc.citation.volume | 101 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordPlus | LEFT-VENTRICULAR HYPERTROPHY | - |
dc.subject.keywordPlus | SUCCESSFUL RENAL-TRANSPLANTATION | - |
dc.subject.keywordPlus | PROGNOSTIC VALUE | - |
dc.subject.keywordPlus | BLOOD-PRESSURE | - |
dc.subject.keywordPlus | DIASTOLIC FUNCTION | - |
dc.subject.keywordPlus | MASS | - |
dc.subject.keywordPlus | IMPACT | - |
dc.subject.keywordPlus | GEOMETRY | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | ECHOCARDIOGRAPHY | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Cardiac & Cardiovascular Systems | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.