Controlled surface functionality of magnetic nanoparticles by layer-by-layer assembled nano-films
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Choi, Daheui | - |
dc.contributor.author | Son, Boram | - |
dc.contributor.author | Park, Tai Hyun | - |
dc.contributor.author | Hong, Jinkee | - |
dc.date.accessioned | 2023-03-08T19:39:46Z | - |
dc.date.available | 2023-03-08T19:39:46Z | - |
dc.date.issued | 2015-04-21 | - |
dc.identifier.issn | 2040-3364 | - |
dc.identifier.issn | 2040-3372 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/64687 | - |
dc.description.abstract | Over the past several years, the preparation of functionalized nanoparticles has been aggressively pursued in order to develop desired structures, compositions, and structural order. Among the various nanoparticles, iron oxide magnetic nanoparticles (MNPs) have shown great promise because the material generated using these MNPs can be used in a variety of biomedical applications and possible bioactive functionalities. In this study, we report the development of various functionalized MNPs (F-MNPs) generated using the layer-by-layer (LbL) self-assembly method. To provide broad functional opportunities, we fabricated F-MNP bio-toolbox by using three different materials: synthetic polymers, natural polymers, and carbon materials. Each of these F-MNPs displays distinct properties, such as enhanced thickness or unique morphologies. In an effort to explore their biomedical applications, we generated basic fibroblast growth factor (bFGF)-loaded F-MNPs. The bFGF-loaded F-MNPs exhibited different release mechanisms and loading amounts, depending on the film material and composition order. Moreover, bFGF-loaded F-MNPs displayed higher biocompatibility and possessed superior proliferation properties than the bare MNPs and pure bFGF, respectively. We conclude that by simply optimizing the building materials and the nanoparticle's film composition, MNPs exhibiting various bioactive properties can be generated. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ROYAL SOC CHEMISTRY | - |
dc.title | Controlled surface functionality of magnetic nanoparticles by layer-by-layer assembled nano-films | - |
dc.type | Article | - |
dc.identifier.doi | 10.1039/c4nr07373h | - |
dc.identifier.bibliographicCitation | NANOSCALE, v.7, no.15, pp 6703 - 6711 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000352277500037 | - |
dc.identifier.scopusid | 2-s2.0-84926430061 | - |
dc.citation.endPage | 6711 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | 6703 | - |
dc.citation.title | NANOSCALE | - |
dc.citation.volume | 7 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordPlus | FIBROBLAST-GROWTH-FACTOR | - |
dc.subject.keywordPlus | IRON-OXIDE NANOPARTICLES | - |
dc.subject.keywordPlus | MULTILAYER FILMS | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | BIOMEDICAL APPLICATIONS | - |
dc.subject.keywordPlus | HYALURONIC-ACID | - |
dc.subject.keywordPlus | GRAPHENE | - |
dc.subject.keywordPlus | STABILITY | - |
dc.subject.keywordPlus | HEPARIN | - |
dc.subject.keywordPlus | RELEASE | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.