Photo-immobilization of bone morphogenetic protein-2 using azidophenyl gelatin on a collagen sheet enhances osteogenesis in a rat calvarial defect model
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Ham, Dae Woong | - |
dc.contributor.author | Jang, Eui Chan | - |
dc.contributor.author | Son, Tae Il | - |
dc.contributor.author | Lee, Tae Jin | - |
dc.contributor.author | Song, Kwang-Sup | - |
dc.date.available | 2019-03-08T12:38:10Z | - |
dc.date.issued | 2016-08 | - |
dc.identifier.issn | 1226-086X | - |
dc.identifier.issn | 1876-794X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/6623 | - |
dc.description.abstract | Twenty-eight rats were randomized into two groups: a control group comprising a collagen sheet with only cast BMP-2; and an experimental group comprising a collagen sheet with BMP-2 photo immobilized using azidophenyl gelatin. Micro-computed tomography analysis revealed that there was more regenerated bone in experimental group at both 4 and 8 weeks. Immunohistochemical analysis revealed that the positively expressed cellular ratio in RUNX2-stained cells were significantly higher in experimental group. These results demonstrate that BMP-2 photo-immobilized using Az-Gel on a collagen sheet shows promising bone regeneration, and the sheet is a good candidate of BMP-2 carrier. (C) 2016 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | Photo-immobilization of bone morphogenetic protein-2 using azidophenyl gelatin on a collagen sheet enhances osteogenesis in a rat calvarial defect model | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jiec.2016.06.021 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY, v.40, pp 177 - 184 | - |
dc.identifier.kciid | ART002134941 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000381834800022 | - |
dc.identifier.scopusid | 2-s2.0-84991013876 | - |
dc.citation.endPage | 184 | - |
dc.citation.startPage | 177 | - |
dc.citation.title | JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY | - |
dc.citation.volume | 40 | - |
dc.type.docType | Review | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Azidophenyl gelatin | - |
dc.subject.keywordAuthor | Az-Gel | - |
dc.subject.keywordAuthor | Bone morphogenetic protein-2 (BMP-2) | - |
dc.subject.keywordAuthor | Osteogenesis | - |
dc.subject.keywordAuthor | Photo-immobilization | - |
dc.subject.keywordAuthor | Rat calvarial defect model | - |
dc.subject.keywordPlus | CRITICAL SIZE DEFECT | - |
dc.subject.keywordPlus | GRAFT SUBSTITUTE | - |
dc.subject.keywordPlus | SEGMENTAL BONE | - |
dc.subject.keywordPlus | DUAL DELIVERY | - |
dc.subject.keywordPlus | GROWTH-FACTOR | - |
dc.subject.keywordPlus | REGENERATION | - |
dc.subject.keywordPlus | BMP-2 | - |
dc.subject.keywordPlus | OSTEOPONTIN | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | RELEASE | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Engineering, Chemical | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.