Synthetic bacteria for the detection and bioremediation of heavy metals
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Thai, Thi Duc | - |
dc.contributor.author | Lim, Wonseop | - |
dc.contributor.author | Na, Dokyun | - |
dc.date.accessioned | 2023-09-01T02:40:49Z | - |
dc.date.available | 2023-09-01T02:40:49Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 2296-4185 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/67444 | - |
dc.description.abstract | Toxic heavy metal accumulation is one of anthropogenic environmental pollutions, which poses risks to human health and ecological systems. Conventional heavy metal remediation approaches rely on expensive chemical and physical processes leading to the formation and release of other toxic waste products. Instead, microbial bioremediation has gained interest as a promising and cost-effective alternative to conventional methods, but the genetic complexity of microorganisms and the lack of appropriate genetic engineering technologies have impeded the development of bioremediating microorganisms. Recently, the emerging synthetic biology opened a new avenue for microbial bioremediation research and development by addressing the challenges and providing novel tools for constructing bacteria with enhanced capabilities: rapid detection and degradation of heavy metals while enhanced tolerance to toxic heavy metals. Moreover, synthetic biology also offers new technologies to meet biosafety regulations since genetically modified microorganisms may disrupt natural ecosystems. In this review, we introduce the use of microorganisms developed based on synthetic biology technologies for the detection and detoxification of heavy metals. Additionally, this review explores the technical strategies developed to overcome the biosafety requirements associated with the use of genetically modified microorganisms. Copyright © 2023 Thai, Lim and Na. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Frontiers Media S.A. | - |
dc.title | Synthetic bacteria for the detection and bioremediation of heavy metals | - |
dc.type | Article | - |
dc.identifier.doi | 10.3389/fbioe.2023.1178680 | - |
dc.identifier.bibliographicCitation | Frontiers in Bioengineering and Biotechnology, v.11 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000979792600001 | - |
dc.identifier.scopusid | 2-s2.0-85153685175 | - |
dc.citation.title | Frontiers in Bioengineering and Biotechnology | - |
dc.citation.volume | 11 | - |
dc.type.docType | Review | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | bioremediation | - |
dc.subject.keywordAuthor | genetically engineered microorganisms | - |
dc.subject.keywordAuthor | heavy metals | - |
dc.subject.keywordAuthor | synthetic biology | - |
dc.subject.keywordAuthor | whole-cell biosensor | - |
dc.subject.keywordPlus | ENHANCED ARSENIC ACCUMULATION | - |
dc.subject.keywordPlus | RECOMBINANT ESCHERICHIA-COLI | - |
dc.subject.keywordPlus | SURFACE DISPLAY | - |
dc.subject.keywordPlus | 2-COMPONENT SYSTEM | - |
dc.subject.keywordPlus | EFFLUX PUMPS | - |
dc.subject.keywordPlus | MERCURY ION | - |
dc.subject.keywordPlus | ZINC | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | STRAIN | - |
dc.subject.keywordPlus | BIOSORPTION | - |
dc.relation.journalResearchArea | Biotechnology & Applied Microbiology | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalWebOfScienceCategory | Biotechnology & Applied Microbiology | - |
dc.relation.journalWebOfScienceCategory | Engineering, Biomedical | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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