Trends in nano-platforms for the treatment of viral infectious diseases
- Authors
- Canlas, K.K.V.; Hong, J.; Chae, J.; Seo, H.W.; Kang, Shinhyuk; Choi, Jonghoon; Park, Hansoo
- Issue Date
- Mar-2023
- Publisher
- Springer
- Keywords
- Nanoparticle Treatment; Nanotechnology; Viral Diseases; Viral Treatment
- Citation
- Korean Journal of Chemical Engineering, v.40, no.4, pp 706 - 713
- Pages
- 8
- Journal Title
- Korean Journal of Chemical Engineering
- Volume
- 40
- Number
- 4
- Start Page
- 706
- End Page
- 713
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/67622
- DOI
- 10.1007/s11814-023-1388-0
- ISSN
- 0256-1115
1975-7220
- Abstract
- Viral diseases have always been a major health issue, from the currently eradicated poliovirus to the still unresolved human immunodeficiency virus, and have since become a recent global threat brought about by the COVID-19 pandemic. Pathogenic viruses easily spread through various means such as contaminated food and water intake, exchange of bodily fluids, or even inhalation of airborne particles mainly due to their miniscule size. Furthermore, viral coats contain virulent proteins which trigger assimilation into target cells on contact through either direct penetration or induction of endocytosis. In some viruses their outer envelope contains masking ligands that create a means of escape from detection of immune cells. To deal with the nanometer size range and biomolecular-based invasion mechanism, nanoparticles are highly suitable for the treatment. The review highlights the progress in nanoparticle technology, particularly viral therapeutics, including therapeutic strategies and existing clinical applications. © 2023, Korean Institute of Chemical Engineering (KIChE).
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