Developing a procedure to extract chenodeoxycholic acid and synthesize ursodeoxycholic acid from pig by-products
DC Field | Value | Language |
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dc.contributor.author | Kim, On You | - |
dc.contributor.author | Lee, Seung Yun | - |
dc.contributor.author | Lee, Da Young | - |
dc.contributor.author | Hur, Sun Jin | - |
dc.date.accessioned | 2023-09-21T05:43:50Z | - |
dc.date.available | 2023-09-21T05:43:50Z | - |
dc.date.issued | 2023-07 | - |
dc.identifier.issn | 2405-8440 | - |
dc.identifier.issn | 2405-8440 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/67694 | - |
dc.description.abstract | This study was conducted to develop simple methods for the extraction of chenodeoxycholic acid (CDCA) and synthesis of ursodeoxycholic acid (UDCA) from pig by-products. The enzymatic method, which uses bile salt hydrolase (BSH) enzymes to extract CDCA, was found to be more efficient than the chemical method. The chemical method, which uses pig by-products, resulted in UDCA amounts of 6.05 mg, 0.51 mg, 3.04 mg, and 1.26 mg in 100 g of the liver, stomach, small intestine, and large intestine, respectively. The amounts of UDCA synthesized/100 g through the chemical and enzymatic methods required to extract CDCA were 3.48 g and 2.22 g, respectively. The procedure developed in this study was simplified by three stages compared to the conventional chemical method of extracting CDCA. Moreover, this study provides a technique that improves the utilization of pig by-products. © 2023 The Authors | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Elsevier Ltd | - |
dc.title | Developing a procedure to extract chenodeoxycholic acid and synthesize ursodeoxycholic acid from pig by-products | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.heliyon.2023.e18313 | - |
dc.identifier.bibliographicCitation | Heliyon, v.9, no.7 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 001048688100001 | - |
dc.identifier.scopusid | 2-s2.0-85166509858 | - |
dc.citation.number | 7 | - |
dc.citation.title | Heliyon | - |
dc.citation.volume | 9 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Bile salt hydrolase enzymes | - |
dc.subject.keywordAuthor | Chenodeoxycholic acid extraction | - |
dc.subject.keywordAuthor | Pig by-products | - |
dc.subject.keywordAuthor | Ursodeoxycholic acid synthesis | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Multidisciplinary Sciences | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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