Efficacy and safety of mucous fistula refeeding in preterm infants: an exploratory randomized controlled trial
DC Field | Value | Language |
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dc.contributor.author | Lee, E.S. | - |
dc.contributor.author | Kim, E.-K. | - |
dc.contributor.author | Shin, S.H. | - |
dc.contributor.author | Jung, Y.H. | - |
dc.contributor.author | Song, I.-G. | - |
dc.contributor.author | Kim, Y.-J. | - |
dc.contributor.author | Kim, H.Y. | - |
dc.contributor.author | Choi, Y.-H. | - |
dc.contributor.author | Moon, K.C. | - |
dc.contributor.author | Kim, B. | - |
dc.date.accessioned | 2023-11-07T04:44:29Z | - |
dc.date.available | 2023-11-07T04:44:29Z | - |
dc.date.issued | 2023-03 | - |
dc.identifier.issn | 1471-2431 | - |
dc.identifier.issn | 1471-2431 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/68488 | - |
dc.description.abstract | BACKGROUND: This study aimed to evaluate whether mucous fistula refeeding (MFR) is safe and beneficial for the growth and intestinal adaptation of preterm infants with enterostomies. METHODS: This exploratory randomized controlled trial enrolled infants born before 35 weeks' gestation with enterostomy. If the stomal output was ≥ 40 mL/kg/day, infants were assigned to the high-output MFR group and received MFR. If the stoma output was < 40 mL/kg/day, infants were randomized to the normal-output MFR group or the control group. Growth, serum citrulline levels, and bowel diameter in loopograms were compared. The safety of MFR was evaluated. RESULTS: Twenty infants were included. The growth rate increased considerably, and the colon diameter was significantly larger after MFR. However, the citrulline levels did not significantly differ between the normal-output MFR and the control group. One case of bowel perforation occurred during the manual reduction for stoma prolapse. Although the association with MFR was unclear, two cases of culture-proven sepsis during MFR were noted. CONCLUSIONS: MFR benefits the growth and intestinal adaptation of preterm infants with enterostomy and can be safely implemented with a standardized protocol. However, infectious complications need to be investigated further. TRIAL REGISTRATION: clinicaltrials.gov NCT02812095, retrospectively registered on June 6, 2016. © 2023. The Author(s). | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | NLM (Medline) | - |
dc.title | Efficacy and safety of mucous fistula refeeding in preterm infants: an exploratory randomized controlled trial | - |
dc.type | Article | - |
dc.identifier.doi | 10.1186/s12887-023-03950-1 | - |
dc.identifier.bibliographicCitation | BMC pediatrics, v.23, no.1, pp 137 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000959495200003 | - |
dc.identifier.scopusid | 2-s2.0-85151200404 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 137 | - |
dc.citation.title | BMC pediatrics | - |
dc.citation.volume | 23 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Citrulline | - |
dc.subject.keywordAuthor | Enterostomy | - |
dc.subject.keywordAuthor | Mucous fistula refeeding | - |
dc.subject.keywordAuthor | Necrotizing enterocolitis | - |
dc.subject.keywordAuthor | Preterm infants | - |
dc.subject.keywordAuthor | Randomized controlled trial | - |
dc.subject.keywordAuthor | Short bowel syndrome | - |
dc.subject.keywordPlus | SHORT-BOWEL SYNDROME | - |
dc.subject.keywordPlus | INTESTINAL REHABILITATION | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | CITRULLINE | - |
dc.relation.journalResearchArea | Pediatrics | - |
dc.relation.journalWebOfScienceCategory | Pediatrics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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