Apigenin’s Therapeutic Potential Against Viral Infection
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, In-Gu | - |
dc.contributor.author | Lee, Jeonghyeon | - |
dc.contributor.author | Hong, So-Hee | - |
dc.contributor.author | Seo, Young-Jin | - |
dc.date.accessioned | 2023-12-05T11:43:05Z | - |
dc.date.available | 2023-12-05T11:43:05Z | - |
dc.date.issued | 2023-10 | - |
dc.identifier.issn | 2768-6701 | - |
dc.identifier.issn | 2768-6698 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/68850 | - |
dc.description.abstract | Several antiviral drugs are clinically approved to treat influenza that is a highly prevalent acute respiratory disease. However, emerging drug-resistant virus strains undermine treatment efficacy, highlighting the exigency for novel antiviral drugs to counter these drug-resistant strains. Plants and their derivates have been historically utilized as medicinal remedies, and extensive studies have evidenced the antiviral potential of phytochemicals. Notably, apigenin is a predominant flavonoid with minimal toxicity and substantial therapeutic effects in various disease models. Despite its many anti-inflammatory, anti-oxidant, anti-cancer, anti-bacterial, and other beneficial bioactivities, existing reviews have yet to focus on apigenin’s antiviral effects. Therefore, this review elucidates apigenin’s therapeutic and antiviral properties in vitro and in vivo, discussing its mode of action and future prospects. Apigenin’s remarkable inhibition by modulating multiple mechanisms against viruses has promising potential for novel plant-derived antiviral drugs and further clinical study developments. © 2023 The Author(s). Published by IMR Press. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | IMR Press Limited | - |
dc.title | Apigenin’s Therapeutic Potential Against Viral Infection | - |
dc.type | Article | - |
dc.identifier.doi | 10.31083/j.fbl2810237 | - |
dc.identifier.bibliographicCitation | Frontiers in Bioscience - Landmark, v.28, no.10 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 001106813700005 | - |
dc.identifier.scopusid | 2-s2.0-85176200411 | - |
dc.citation.number | 10 | - |
dc.citation.title | Frontiers in Bioscience - Landmark | - |
dc.citation.volume | 28 | - |
dc.type.docType | Review | - |
dc.publisher.location | 싱가폴 | - |
dc.subject.keywordAuthor | 4′,5,7-trihydroxyflavone | - |
dc.subject.keywordAuthor | antiviral drugs | - |
dc.subject.keywordAuthor | flavonoids | - |
dc.subject.keywordAuthor | influenza | - |
dc.subject.keywordAuthor | phytochemicals | - |
dc.subject.keywordPlus | CANCER STEM-CELLS | - |
dc.subject.keywordPlus | INFLUENZA-A VIRUS | - |
dc.subject.keywordPlus | EPITHELIAL-MESENCHYMAL TRANSITIONS | - |
dc.subject.keywordPlus | PRIMARY CILIA | - |
dc.subject.keywordPlus | ENTEROVIRUS 71 | - |
dc.subject.keywordPlus | CYCLOOXYGENASE-2 EXPRESSION | - |
dc.subject.keywordPlus | ANTIINFLAMMATORY MECHANISMS | - |
dc.subject.keywordPlus | ANTIVIRAL ACTIVITY | - |
dc.subject.keywordPlus | POSTMITOTIC CELLS | - |
dc.subject.keywordPlus | ENDOTHELIAL-CELLS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.