Determination of Mycoplasma hyopneumoniae-Specific IgG, IgG1, and IgG2a Titers in BALB/c Mice Induced by Mineral Oil-Based Oil-in-Water Emulsion Adjuvants Prepared Using a Self-Emulsifying Drug Delivery System
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bastola, Rakesh | - |
dc.contributor.author | Seo, Jo-Eun | - |
dc.contributor.author | Noh, Gyubin | - |
dc.contributor.author | Keum, Taekwang | - |
dc.contributor.author | Kim, Ju Hun | - |
dc.contributor.author | Shin, Jong Il | - |
dc.contributor.author | Lee, Sooyeun | - |
dc.contributor.author | Lee, Sangkil | - |
dc.date.accessioned | 2024-01-08T06:57:56Z | - |
dc.date.available | 2024-01-08T06:57:56Z | - |
dc.date.issued | 2019-01 | - |
dc.identifier.issn | 1530-9932 | - |
dc.identifier.issn | 1522-1059 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/69428 | - |
dc.description.abstract | We prepared mineral oil-based emulsion adjuvants by employing simple self-emulsifying drug delivery system (SEDDS). Mineral oil emulsions (3%, 5%, and 7%) were prepared using deionized water and C-971P NF and C-940 grade carbomer solutions with concentrations 0.01% (w/v) and 0.02% (w/v). In total, 15 emulsions were prepared and mixed with a solution containing inactivated Mycoplasma hyopneumoniae (J101 strain) antigen and porcine circovirus type 2 antigen to prepare vaccines. Droplet sizes in the submicron range and zeta potential values between -40 and 0mV were maintained by most emulsion adjuvants for a period of 6months. Emulsion adjuvants were regarded safe, and their M. hyopneumoniae-specific IgG, IgG1, and IgG2a titers were either better or comparable to those of aluminum gel. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Determination of Mycoplasma hyopneumoniae-Specific IgG, IgG1, and IgG2a Titers in BALB/c Mice Induced by Mineral Oil-Based Oil-in-Water Emulsion Adjuvants Prepared Using a Self-Emulsifying Drug Delivery System | - |
dc.type | Article | - |
dc.identifier.doi | 10.1208/s12249-018-1245-3 | - |
dc.identifier.bibliographicCitation | AAPS PHARMSCITECH, v.20, no.1 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000454994400006 | - |
dc.identifier.scopusid | 2-s2.0-85059475479 | - |
dc.citation.number | 1 | - |
dc.citation.title | AAPS PHARMSCITECH | - |
dc.citation.volume | 20 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | self-emulsifying drug delivery system | - |
dc.subject.keywordAuthor | mineral oil-based emulsion adjuvant | - |
dc.subject.keywordAuthor | Mycoplasma hyopneumoniae-specific IgG | - |
dc.subject.keywordAuthor | IgG1 | - |
dc.subject.keywordAuthor | and IgG2a titers | - |
dc.subject.keywordPlus | FORMULATION | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.