Association between hypertension and myosteatosis evaluated by abdominal computed tomography
DC Field | Value | Language |
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dc.contributor.author | Jung, H.N. | - |
dc.contributor.author | Cho, Y.K. | - |
dc.contributor.author | Kim, H.S. | - |
dc.contributor.author | Kim, E.H. | - |
dc.contributor.author | Lee, M.J. | - |
dc.contributor.author | Lee, W.J. | - |
dc.contributor.author | Kim, H.-K. | - |
dc.contributor.author | Jung, C.H. | - |
dc.date.accessioned | 2024-01-09T15:03:45Z | - |
dc.date.available | 2024-01-09T15:03:45Z | - |
dc.date.issued | 2023-04 | - |
dc.identifier.issn | 0916-9636 | - |
dc.identifier.issn | 1348-4214 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/70589 | - |
dc.description.abstract | Few studies have examined the relationship between myosteatosis and hypertension, and no studies have enrolled an Asian population. Existing studies also found discordant results, possibly due to the use of conventional myosteatosis indices that are not sufficiently reliable and representative. Therefore, we investigated the association between myosteatosis and hypertension in Asian individuals using novel, objective computed tomography (CT) markers. The total abdominal muscle area (TAMA) was determined from abdominal CT scans taken at the L3 level. Based on the mean CT attenuation, the TAMA was divided into intramuscular adipose tissue and skeletal muscle area (SMA), which was further segmented into normal attenuation muscle area (NAMA) and low attenuation muscle area (LAMA). Among SMA/body mass index (BMI), NAMA/BMI, LAMA/BMI, and the NAMA/TAMA index, NAMA/BMI was chosen through receiver operating characteristic curves as the best predictive marker for hypertension. The hypertension risk for each quartile of NAMA/BMI was calculated by logistic regression analysis. Among the 19,766 participants, 40.3% of men and 23.8% of women had hypertension. People with hypertension showed unhealthier myosteatosis profiles than normotensive controls. Similarly, a lower NAMA/BMI was significantly associated with a greater hypertension risk. The lowest quartile group of NAMA/BMI exhibited 2.3- and 2.6-fold higher risks of hypertension than the highest quartile in men and women, respectively. In conclusion, advanced myosteatosis assessed by abdominal CT was significantly correlated with a higher risk of hypertension. Improving myosteatosis may be a new approach for preventing cardiovascular diseases, including hypertension. [Figure not available: see fulltext.]. © 2023, The Author(s), under exclusive licence to The Japanese Society of Hypertension. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Nature | - |
dc.title | Association between hypertension and myosteatosis evaluated by abdominal computed tomography | - |
dc.type | Article | - |
dc.identifier.doi | 10.1038/s41440-022-01157-y | - |
dc.identifier.bibliographicCitation | Hypertension Research, v.46, no.4, pp 845 - 855 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000913487500002 | - |
dc.identifier.scopusid | 2-s2.0-85146169967 | - |
dc.citation.endPage | 855 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 845 | - |
dc.citation.title | Hypertension Research | - |
dc.citation.volume | 46 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Computed tomography | - |
dc.subject.keywordAuthor | Hypertension | - |
dc.subject.keywordAuthor | Myosteatosis | - |
dc.subject.keywordAuthor | Skeletal muscle area | - |
dc.subject.keywordAuthor | Skeletal muscle quality | - |
dc.subject.keywordPlus | INTERMUSCULAR ADIPOSE-TISSUE | - |
dc.subject.keywordPlus | BODY SKELETAL-MUSCLE | - |
dc.subject.keywordPlus | INSULIN-RESISTANCE | - |
dc.subject.keywordPlus | FAT | - |
dc.subject.keywordPlus | ATTENUATION | - |
dc.subject.keywordPlus | RISK | - |
dc.subject.keywordPlus | STRENGTH | - |
dc.subject.keywordPlus | VOLUMES | - |
dc.subject.keywordPlus | QUALITY | - |
dc.subject.keywordPlus | LUMBAR | - |
dc.relation.journalResearchArea | Cardiovascular System & Cardiology | - |
dc.relation.journalWebOfScienceCategory | Peripheral Vascular Disease | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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